Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997632 | 0.86 | SMN1; SMN2 (0.44) | LMNASMN1; SMN2NPSR1MAPTL3MBTL1 | |
| SCHEMBL7997644 | 0.84 | LMNA (0.44) | LMNASMN1; SMN2NPSR1MAPTL3MBTL1 | |
| SCHEMBL7983888 | 0.84 | LMNA (0.43) | LMNASMN1; SMN2NPSR1MAPTL3MBTL1 | |
| SCHEMBL7997629 | 0.82 | LMNA (0.47) | LMNASMN1; SMN2NPSR1MAPTL3MBTL1 | |
| SCHEMBL7995873 | 0.82 | LMNA (0.45) | LMNASMN1; SMN2NPSR1MAPTL3MBTL1 | |
| SCHEMBL7997738 | 0.80 | LMNA (0.41) | LMNASMN1; SMN2NPSR1MAPTL3MBTL1 | |
| SCHEMBL7997378 | 0.80 | LMNA (0.41) | LMNASMN1; SMN2NPSR1MAPTL3MBTL1 | |
| SCHEMBL7983744 | 0.80 | LMNA (0.43) | LMNASMN1; SMN2NPSR1MAPTL3MBTL1 | |
| SCHEMBL7995758 | 0.80 | LMNA (0.43) | LMNASMN1; SMN2NPSR1MAPTL3MBTL1 | |
| SCHEMBL7983644 | 0.79 | LMNA (0.42) | LMNASMN1; SMN2NPSR1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | claimed |
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |