Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997738 | 0.87 | LMNA (0.41) | LMNASMN1; SMN2MAPTNPSR1L3MBTL1 | |
| SCHEMBL7997632 | 0.85 | SMN1; SMN2 (0.44) | LMNASMN1; SMN2MAPTNPSR1L3MBTL1 | |
| SCHEMBL7994556 | 0.83 | HDAC1 (0.41) | LMNASMN1; SMN2MAPTTSHRALDH1A1 | |
| SCHEMBL7997644 | 0.82 | LMNA (0.44) | LMNASMN1; SMN2MAPTNPSR1L3MBTL1 | |
| SCHEMBL7995758 | 0.81 | LMNA (0.43) | LMNASMN1; SMN2MAPTNPSR1L3MBTL1 | |
| SCHEMBL7997882 | 0.80 | LMNA (0.43) | LMNASMN1; SMN2MAPTNPSR1L3MBTL1 | |
| SCHEMBL7995873 | 0.80 | LMNA (0.45) | LMNASMN1; SMN2MAPTNPSR1L3MBTL1 | |
| SCHEMBL7994551 | 0.79 | HDAC1 (0.39) | LMNASMN1; SMN2TSHRALDH1A1HDAC1 | |
| SCHEMBL7997629 | 0.79 | LMNA (0.47) | LMNASMN1; SMN2MAPTNPSR1L3MBTL1 | |
| SCHEMBL7983888 | 0.78 | LMNA (0.43) | LMNASMN1; SMN2MAPTNPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |