Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | RGS12 | O14924 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28373111 | 1.00 | USP2 (0.44) | USP2POLBRGS12CYP3A4CYP2C9 | |
| SCHEMBL2309888 | 0.88 | CTSD (0.46) | USP2POLBRGS12CYP3A4CYP2C9 | |
| SCHEMBL2309890 | 0.88 | CTSD (0.46) | USP2POLBRGS12CYP3A4CYP2C9 | |
| SCHEMBL13957558 | 0.84 | HSD17B10 (0.45) | USP2POLBRGS12CYP3A4CYP2C9 | |
| SCHEMBL7302384 | 0.84 | HTT (0.46) | USP2POLBRGS12CYP3A4CYP2C9 | |
| SCHEMBL29519833 | 0.84 | HSD17B10 (0.49) | USP2POLBRGS12CYP3A4CYP2C9 | |
| SCHEMBL429259 | 0.83 | KIF11 (0.45) | POLBKIF11 | |
| SCHEMBL1571535 | 0.82 | PCNA (0.51) | USP2RGS12CYP3A4CYP2C9PKM | |
| SCHEMBL1571537 | 0.82 | PCNA (0.51) | USP2RGS12CYP3A4CYP2C9PKM | |
| SCHEMBL2898766 | 0.82 | KIF11 (0.52) | USP2POLBRGS12CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000015606-A1 | SUBSTITUTED N-ARYL-O-ALKYL-CARBAMATES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-03-23 | — | — | WO | disclosed |