Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 6/20 | 0.42 |
| ▸ | HTR1D | P28221 | 6/20 | 0.42 |
| ▸ | HTR1B | P28222 | 6/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16952952 | 0.88 | CNR1 (0.43) | TP53 | |
| SCHEMBL16953779 | 0.82 | MAPT (0.45) | SMN1; SMN2MAPTTP53CYP1A2CYP2D6 | |
| SCHEMBL29313102 | 0.80 | PLA2G2A (0.45) | MAPTTP53 | |
| SCHEMBL1071885 | 0.80 | TP53 (0.50) | MAPTKDM4ETP53CYP1A2CYP3A4 | |
| SCHEMBL14331832 | 0.80 | PLA2G2A (0.48) | TP53CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL16961617 | 0.79 | TP53 (0.45) | SMN1; SMN2MAPK1KDM4ETP53CYP1A2 | |
| SCHEMBL1047171 | 0.77 | HTR2A (0.62) | GLASMN1; SMN2HTR2AMAPK1CYP3A4 | |
| SCHEMBL15502971 | 0.77 | TAAR1 (0.56) | HTR2AMAPK1KDM4ECYP1A2TAAR1 | |
| SCHEMBL2911039 | 0.77 | TAAR1 (0.62) | GLASMN1; SMN2CYP2D6TAAR1 | |
| SCHEMBL16960770 | 0.77 | ALDH1A1 (0.40) | SMN1; SMN2KDM4ETP53CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009113320-A1 | MMP INHIBITOR | 株式会社ヤクルト本社 (JP) | 2009-09-17 | — | — | WO | disclosed |