Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7998442 | 0.75 | GAA (0.46) | ALDH1A1HPGDCA2KDM4EMAPT | |
| SCHEMBL7994379 | 0.73 | PABPC1 (0.38) | ALDH1A1MAPTKMT2A | |
| SCHEMBL7978062 | 0.72 | CA12 (0.48) | ALDH1A1GLACA2PDE3BPDE3A | |
| SCHEMBL8001777 | 0.72 | SCN9A (0.33) | SMN1; SMN2KMT2A | |
| SCHEMBL27501325 | 0.72 | ALDH1A1 (0.51) | ALDH1A1GLAF2HPGDCA2 | |
| SCHEMBL9968617 | 0.70 | PDE10A (0.62) | ALDH1A1HPGDKDM4EMAPTKMT2A | |
| SCHEMBL7590790 | 0.69 | ALDH1A1 (0.68) | ALDH1A1GLAF2HPGDCA2 | |
| SCHEMBL28814899 | 0.68 | ALDH1A1 (0.67) | ALDH1A1GLAF2HPGDCA2 | |
| SCHEMBL3150403 | 0.68 | ALDH1A1 (0.67) | ALDH1A1GLAF2HPGDCA2 | |
| SCHEMBL7594210 | 0.68 | ALDH1A1 (0.62) | ALDH1A1GLAF2HPGDCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055140-A1 | ISOTHIAZOLE DERIVATIVES AND THEIR USE AS PESTICIDES | SYNGENTA LIMITED (GB) | 2001-08-02 | — | — | WO | disclosed |