Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15079864 | 0.86 | L3MBTL1 (0.49) | MAPTHPGDSMN1; SMN2PPARGL3MBTL1 | |
| SCHEMBL7998391 | 0.86 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDSMN1; SMN2LMNA | |
| SCHEMBL7996933 | 0.80 | HPGD (0.62) | HPGDPPARGPTPN1 | |
| SCHEMBL7987959 | 0.80 | HPGD (0.62) | HPGDPPARGPTPN1 | |
| SCHEMBL7987761 | 0.78 | ALDH1A1 (0.55) | ALDH1A1MAPTHPGDSMN1; SMN2LMNA | |
| SCHEMBL7996977 | 0.75 | ALDH1A1 (0.46) | ALDH1A1MAPTHPGDSMN1; SMN2LMNA | |
| SCHEMBL3171854 | 0.75 | TAAR1 (0.41) | ALDH1A1MAPTLMNAL3MBTL1KDM4E | |
| SCHEMBL8000471 | 0.75 | ALDH1A1 (0.52) | ALDH1A1MAPTHPGDSMN1; SMN2LMNA | |
| SCHEMBL7800280 | 0.73 | TAAR1 (0.56) | ALDH1A1MAPTHPGDSMN1; SMN2LMNA | |
| SCHEMBL9311261 | 0.72 | RAB9A (0.55) | ALDH1A1MAPTHPGDSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288096-B1 | ANTIDIABETIC AGENTS, HYPOTENSIVE AGENTS, AND ANTICHOLESTEROL AGENTS | ASTRAZENECA AB (SE) | 2001-09-11 | — | — | US | disclosed |
| EP-0991632-A1 | NEW THIAZOLIDINEDIONE, OXAZOLIDINEDIONE AND OXADIAZOLIDINEDIONE DERIVATIVES | Astra Aktiebolag (SE) | 2000-04-12 | — | — | EP | disclosed |
| WO-1998057941-A1 | NEW THIAZOLIDINEDIONE, OXAZOLIDINEDIONE AND OXADIAZOLIDINEDIONE DERIVATIVES | ASTRA AKTIEBOLAG (SE) | 1998-12-23 | — | — | WO | disclosed |