Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | GPR52 | Q9Y2T5 | 3/20 | 0.33 |
| ▸ | KDM1A | O60341 | 3/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.31 |
| ▸ | PTPRB | P23467 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28133385 | 0.81 | GPR52 (0.44) | GPR52PTPRB | |
| SCHEMBL17713470 | 0.79 | PARP1 (0.34) | KIF11KDM1AKCNH2KDM1BPTPRB | |
| SCHEMBL30917473 | 0.79 | KDM1A (0.33) | KDM1AKCNH2KDM1BPARP1 | |
| SCHEMBL2302020 | 0.76 | KDM4E (0.47) | KIF11KDM1ACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL29410056 | 0.76 | KDM4E (0.47) | KIF11KDM1ACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL7994529 | 0.76 | TRPV4 (0.46) | KCNH2 | |
| SCHEMBL2298160 | 0.74 | TDP1 (0.39) | KIF11KDM1ACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL29410058 | 0.74 | TDP1 (0.39) | KIF11KDM1ACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL14555727 | 0.74 | IGF1R (0.40) | KDM1AKCNH2KDM1BPARP1 | |
| SCHEMBL1128476 | 0.74 | TAAR1 (0.52) | CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001051494-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-07-19 | — | — | WO | disclosed |