Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 12/20 | 0.49 |
| ▸ | F13A1 | P00488 | 9/20 | 0.49 |
| ▸ | TGM1 | P22735 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.48 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.48 |
| ▸ | STS | P08842 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.44 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL308426 | 0.87 | TGM2 (0.53) | TGM2F13A1TGM1MAPTGPR119 | |
| SCHEMBL309691 | 0.86 | EPHX2 (0.55) | TGM2F13A1TGM1MAPTGPR119 | |
| SCHEMBL309243 | 0.82 | TGM2 (0.64) | TGM2F13A1TGM1MAPTGPR119 | |
| SCHEMBL2312877 | 0.81 | LMNA (0.62) | TGM2F13A1TGM1STSTGFBR1 | |
| SCHEMBL13076730 | 0.79 | GPR119 (0.53) | MAPTGPR119STSMEN1ALDH1A1 | |
| SCHEMBL5442261 | 0.75 | TGM2 (0.52) | TGM2F13A1TGM1GPR119TGM3 | |
| SCHEMBL31142873 | 0.75 | GPR119 (0.69) | MAPTGPR119STSMEN1ALDH1A1 | |
| SCHEMBL3922455 | 0.75 | GPR119 (0.69) | MAPTGPR119STSMEN1ALDH1A1 | |
| SCHEMBL29060791 | 0.74 | TGM2 (0.64) | TGM2F13A1TGM1 | |
| SCHEMBL13261277 | 0.74 | GPR119 (0.59) | MAPTGPR119MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010007074-A1 | PYRAZOLO [1, 5-A] PYRIMIDINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2010-01-21 | — | — | WO | disclosed |