SCHEMBL7998564

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3834593	0.93	HDAC1 (0.47)	HDAC1HDAC3HDAC2NCOR2HTR5A
	SCHEMBL8001893	0.92	HDAC1 (0.47)	HDAC1HDAC3HDAC2NCOR2HTR5A
	SCHEMBL1496862	0.90	HTR5A (0.40)	HDAC1HDAC3HDAC2NCOR2HTR5A
	SCHEMBL3831002	0.88	HDAC1 (0.51)	HDAC1HDAC3HDAC2NCOR2HTR5A
	SCHEMBL11892983	0.88	HDAC1 (0.40)	HDAC1HDAC3HDAC2NCOR2HDAC6
	SCHEMBL1497043	0.86	HIF1A (0.42)	HDAC1HTR5ASLC6A4CTSK
	SCHEMBL1496875	0.85	HTR5A (0.39)	HDAC1HDAC3HDAC2NCOR2HTR5A
	SCHEMBL1496983	0.85	HDAC1 (0.45)	HDAC1HDAC3HDAC2NCOR2HTR5A
	SCHEMBL3832752	0.85	HDAC1 (0.48)	HDAC1HDAC3HDAC2NCOR2HDAC6
	SCHEMBL1496892	0.85	CTSK (0.38)	HDAC1HDAC3HDAC2NCOR2HTR5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.