Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.48 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8003104 | 0.92 | MGLL (0.46) | MGLLCYP46A1HRH3HCRTR1HCRTR2 | |
| SCHEMBL7999939 | 0.92 | MGLL (0.52) | MGLLCYP46A1HRH3KMT2APLA2G2A | |
| SCHEMBL7997634 | 0.91 | NPC1 (0.45) | MGLLCYP46A1HRH3HCRTR1HCRTR2 | |
| SCHEMBL7996195 | 0.85 | NPC1 (0.42) | MGLLCYP46A1HRH3LMNAMAPT | |
| SCHEMBL7996342 | 0.84 | HCRTR1 (0.47) | HRH3HCRTR1HCRTR2LMNAALDH1A1 | |
| SCHEMBL7999739 | 0.84 | NPC1 (0.47) | MGLLCYP46A1HRH3LMNAPLA2G2A | |
| SCHEMBL7996149 | 0.82 | HCRTR1 (0.46) | HCRTR1HCRTR2LMNAALDH1A1MAPT | |
| SCHEMBL7999727 | 0.79 | HCRTR1 (0.46) | HRH3HCRTR1HCRTR2LMNAALDH1A1 | |
| SCHEMBL7074772 | 0.79 | MGLL (0.66) | MGLLLMNAALDH1A1MAPTMEN1 | |
| SCHEMBL7999778 | 0.77 | SLC2A1 (0.43) | HRH3HCRTR1HCRTR2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000008005-A2 | PIPERAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-02-17 | — | — | WO | disclosed |