SCHEMBL7999872

SCHEMBL7999872

CC(C)(C)OC(=O)C1C2C=CC1CC2

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.46
APEX1 P27695 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
MAPK1 P28482 1/20 0.39
NFKB1 P19838 2/20 0.35
NFKB2 Q00653 2/20 0.35
RELA Q04206 2/20 0.35
HRH3 Q9Y5N1 1/20 0.35
CHRM2 P08172 1/20 0.34
CHRM1 P11229 1/20 0.34
CHRM3 P20309 1/20 0.34
GPR119 Q8TDV5 6/20 0.34
HPGD P15428 1/20 0.31
BTK Q06187 1/20 0.31
PREP P48147 1/20 0.30
DGAT1 O75907 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1409756 0.83 ALDH1A1 (0.41) POLBAPEX1TDP1MAPK1NFKB1
SCHEMBL18906481 0.80 MAPK1 (0.37) POLBAPEX1TDP1MAPK1NFKB1
SCHEMBL13898963 0.80 MAPK1 (0.37) POLBAPEX1TDP1MAPK1NFKB1
SCHEMBL5837416 0.77 POLB (0.51) POLBAPEX1TDP1
SCHEMBL686094 0.77 MAPK1 (0.38) POLBMAPK1NFKB1NFKB2RELA
SCHEMBL3150000 0.77 POLB (0.51) POLBAPEX1TDP1
SCHEMBL5838089 0.77 ALDH1A1 (0.37) POLBMAPK1NFKB1NFKB2RELA
SCHEMBL5838085 0.77 ALDH1A1 (0.37) POLBMAPK1NFKB1NFKB2RELA
SCHEMBL31092878 0.76 MAPK1 (0.34) POLBTDP1MAPK1NFKB1NFKB2
SCHEMBL882850 0.75 MAPK1 (0.40) MAPK1NFKB1NFKB2RELAHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6291131-B1 ADDITION POLYMERIZATION OF MONOMERS TO FORM PHOTORESISTS COPOLYMER HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) 2001-09-18 US disclosed