SCHEMBL8000107

SCHEMBL8000107

CCN(CC)CC.NC(O)=S.NC(O)=S

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
CYP2C9 P11712 2/20 0.40
HPGD P15428 2/20 0.40
HSD17B10 Q99714 2/20 0.40
EHMT2 Q96KQ7 3/20 0.36
EHMT1 Q9H9B1 3/20 0.36
ABCB11 O95342 2/20 0.36
HTT P42858 2/20 0.36
GSDMD P57764 2/20 0.36
CA12 O43570 2/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA4 P22748 2/20 0.36
CA9 Q16790 2/20 0.36
CYP2E1 P05181 1/20 0.36
PTGS1 P23219 1/20 0.36
PHGDH O43175 2/20 0.35
MGLL Q99685 2/20 0.35
TSHR P16473 2/20 0.35
NPSR1 Q6W5P4 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5671521 1.00 ALDH1A1 (0.40) ALDH1A1CYP2C9HPGDHSD17B10EHMT2
SCHEMBL2341351 0.87 ALDH1A1 (0.33) ALDH1A1CYP2C9HPGDHSD17B10NPSR1
SCHEMBL29111587 0.87 EHMT2 (0.40) ALDH1A1CYP2C9HPGDHSD17B10EHMT2
Pyrazine SCHEMBL8862630 0.84 MAPK1 (0.33) ALDH1A1CYP2C9HPGDHSD17B10
SCHEMBL8000101 0.84 ALDH1A1 (0.50) ALDH1A1CYP2C9HPGDHSD17B10EHMT2
SCHEMBL8775194 0.83 ALDH1A1 (0.42) ALDH1A1CYP2C9HPGDHSD17B10EHMT2
Hydrogen Peroxide SCHEMBL139127 0.82 ALDH1A1 (0.36) ALDH1A1CYP2C9HPGDHSD17B10EHMT2
Hydrogen Peroxide SCHEMBL139129 0.82
SCHEMBL27379707 0.81 CHRM2 (0.35) ALDH1A1CYP2C9HPGDHSD17B10HTT
Carbamic Acid SCHEMBL9456468 0.80 ACHE (0.47) ALDH1A1HPGDHTTCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108779213-A Methacrylic resin composition and formed body 旭化成株式会社 2018-11-09 CN disclosed
CN-108627979-A Head-mounted display component 旭化成株式会社 2018-10-09 CN disclosed
CN-108350125-A METHACRYLIC RESIN, METHACRYLIC RESIN COMPOSITION, FILM, AND PRODUCTION METHOD 旭化成株式会社 2018-07-31 CN disclosed
CN-107540779-A Methacrylic resin composition, the manufacture method of the Methacrylic resin composition, particle and formed body 旭化成株式会社 2018-01-05 CN disclosed
CN-105949695-A METHACRYLIC RESIN COMPOSITION, METHOD FOR PRODUCING THE SAME, AND MOLDED ARTICLE 旭化成株式会社 2016-09-21 CN disclosed
US-6287821-B1 NUCLEOTIDE HAVING CLEAVABLE LINKING GROUP, SPACER LINKING GROUP, AND REPORTER MOLECULE ATTACHED AT 3' POSITION; REPORTER MOLECULE HAS GREATER FLUORESCENCE WHEN UNATTACHED FROM NUCLEOTIDE; SENSITIVE AMPLIFICATION OF SIGNAL ORCHID BIOSCIENCES, INC. 2001-09-11 US disclosed
WO-1999064437-A1 NUCLEOTIDE ANALOGUES WITH 3'-PRO-FLUORESCENT FLUOROPHORES IN NUCLEIC ACID SEQUENCE ANALYSIS ORCHID BIOSCIENCES, INC. (US) 1999-12-16 WO disclosed
US-5605663-A Aromatic acids CIBA-GEIGY CORPORATION (US) 1997-02-25 US disclosed
US-5587461-A Aromatic acids CIBA-GEIGY CORPORATION (US) 1996-12-24 US disclosed
US-5382659-A Aromatic acids CIBA-GEIGY CORP. (US) 1995-01-17 US disclosed
US-5229503-A Lysine-n-amino reactive and cysteine-mercapto reactive azo dyes CIBA-GEIGY CORPORATION (US) 1993-07-20 US disclosed
US-5030368-A Reacting amine or metal dithiocarbamate salt with organophosphorodichloridite MOBIL OIL CORPORATION (US) 1991-07-09 US disclosed
US-4970022-A ISOTHIOCYANATES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1990-11-13 US disclosed
EP-0126883-B1 LIQUID CRYSTALLINE CYCLOHEXYLBENZENE DERIVATIVES, THEIR PREPARATION AND THE LIQUID CRYSTAL COMPOSITIONS CONTAINING THEM Wojskowa Akademia Techniczna im. Jaroslawa Dabrowskiego (PL) 1987-03-11 EP disclosed
US-4610954-A ANTIFOGGING AGENTS FUJI PHOTO FILM CO., LTD. (JP) 1986-09-09 US disclosed
EP-0126883-A1 Liquid crystalline cyclohexylbenzene derivatives, their preparation and the liquid crystal compositions containing them Wojskowa Akademia Techniczna im. Jaroslawa Dabrowskiego (PL) 1984-12-05 EP disclosed