Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.49 |
| ▸ | HTR2A | P28223 | 9/20 | 0.49 |
| ▸ | HTR2C | P28335 | 9/20 | 0.49 |
| ▸ | HTR2B | P41595 | 9/20 | 0.49 |
| ▸ | DRD2 | P14416 | 9/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6629689 | 0.81 | SIGMAR1 (0.53) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL3493108 | 0.74 | SMN1; SMN2 (0.43) | SIGMAR1CYP2C19ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL6112888 | 0.72 | SIGMAR1 (0.46) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL29447988 | 0.72 | SIGMAR1 (0.57) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL3054003 | 0.72 | SIGMAR1 (0.57) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL11242114 | 0.71 | SIGMAR1 (0.53) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL12086604 | 0.71 | SIGMAR1 (0.49) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL14358027 | 0.70 | SIGMAR1 (0.56) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL28153577 | 0.70 | NPSR1 (0.46) | SIGMAR1HTR2AHTR2CHTR2BMAPT | |
| SCHEMBL31237962 | 0.70 | SIGMAR1 (0.54) | SIGMAR1HTR2AHTR2CHTR2BDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6287749-B1 | FOR UNSATURATED COMPOUNDS | FIRST CHEMICAL CORPORATION | 2001-09-11 | — | — | US | disclosed |
| EP-0980393-A1 | BIRADICAL PHOTOINITIATORS | First Chemical Corporation (US) | 2000-02-23 | — | — | EP | disclosed |
| WO-1998050437-A1 | BIRADICAL PHOTOINITIATORS | FIRST CHEMICAL CORPORATION (US) | 1998-11-12 | — | — | WO | disclosed |
| EP-0284359-A1 | 1,4-Disubstituted piperazine compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1988-09-28 | — | — | EP | disclosed |