Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CCR9 | P51686 | 3/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8005114 | 0.88 | MAPT (0.44) | MEN1KMT2AMAPTMAPK1TDP1 | |
| SCHEMBL8005176 | 0.86 | TDP1 (0.43) | MEN1KMT2AMAPTMAPK1TDP1 | |
| SCHEMBL8002136 | 0.86 | MAPT (0.43) | MEN1KMT2AMAPTMAPK1TDP1 | |
| SCHEMBL8002481 | 0.86 | SRD5A2 (0.49) | MEN1KMT2AMAPTMAPK1TDP1 | |
| SCHEMBL7989865 | 0.85 | MAPT (0.43) | MEN1KMT2AMAPTMAPK1TDP1 | |
| SCHEMBL8000191 | 0.83 | CCR9 (0.39) | KMT2ANPSR1KDM4ECCR9SRD5A2 | |
| SCHEMBL7483341 | 0.83 | MAPT (0.46) | MEN1KMT2AMAPTMAPK1TDP1 | |
| SCHEMBL8002367 | 0.81 | MAPT (0.40) | MEN1KMT2AMAPTMAPK1TDP1 | |
| SCHEMBL8001948 | 0.81 | L3MBTL1 (0.44) | MEN1KMT2AMAPTMAPK1TDP1 | |
| SCHEMBL7841868 | 0.79 | MAPK1 (0.54) | MEN1KMT2AMAPTMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294536-B1 | CONTROL OF PROTOZOA AND REDUCTION IN THE INCIDENCE OF ASSOCIATED DISEASES AND DEATH AND CONSEQUENT IMPROVEMENT IN RETARDED GROWTH AND GENERAL CONDITION AND PREVENTING DECREASE GROWTH AND GENERAL CONDITION | TAKEDA SCHERING-PLOUGH ANIMAL HEALTH K.K. (JP) | 2001-09-25 | — | — | US | disclosed |