Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8002481 | 0.85 | SRD5A2 (0.49) | MAPK1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL7483341 | 0.84 | MAPT (0.46) | MAPK1KMT2AMAOBMAOAALDH1A1 | |
| SCHEMBL7840421 | 0.82 | CYP1A2 (0.51) | MAPK1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL7922602 | 0.81 | HGFAC (0.42) | MAPK1KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL8000281 | 0.79 | MEN1 (0.46) | MAPK1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL7838560 | 0.79 | KMT2A (0.56) | KMT2AMAOBMAOAALDH1A1LMNA | |
| SCHEMBL7480367 | 0.79 | ALDH1A1 (0.50) | MAPK1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL8005114 | 0.78 | MAPT (0.44) | MAPK1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL8002334 | 0.78 | VCAM1 (0.49) | KMT2AALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL27459498 | 0.78 | KMT2A (0.55) | KMT2AMAOBMAOALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737672-B1 | Method of producing triazine derivatives | TAKEDA SCHERING PLOUGH ANIMAL (JP) | 2001-10-04 | — | — | EP | disclosed |
| US-6211178-B1 | ANTIPROTOZOA AGENTS FOR COCCIDIOIDES; CYCLIZATION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| US-5994355-A | ANTIPROTOZOA AGENTS, PARASITICIDE; VETERINARY MEDICINE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-30 | — | — | US | disclosed |
| EP-0737672-A2 | Method of producing triazine derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-10-16 | — | — | EP | disclosed |