Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | GLA | P06280 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.47 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.47 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 2/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3252424 | 0.82 | ALDH1A1 (0.45) | ALDH1A1GLAKDM4ERAB9AHPGD | |
| SCHEMBL3482953 | 0.81 | ALDH1A1 (0.44) | ALDH1A1GLAKDM4ERAB9AHPGD | |
| SCHEMBL7094916 | 0.80 | GAA (0.54) | ALDH1A1GLAKDM4ERAB9AHPGD | |
| SCHEMBL20509016 | 0.80 | TUBB4A (0.42) | ALDH1A1KDM4ERAB9AHPGDKMT2A | |
| SCHEMBL3482649 | 0.80 | ALDH1A1 (0.43) | ALDH1A1GLAKDM4ERAB9AHPGD | |
| SCHEMBL28934981 | 0.79 | TUBB4A (0.41) | ALDH1A1KDM4ERAB9AHPGDKMT2A | |
| Ammonia Solution, Strong SCHEMBL28934994 | 0.79 | TUBB4A (0.41) | ALDH1A1KDM4EHPGDKMT2ALMNA | |
| SCHEMBL28935137 | 0.79 | TUBB4A (0.41) | ALDH1A1KDM4ERAB9AHPGDKMT2A | |
| SCHEMBL28935121 | 0.79 | TUBB4A (0.41) | ALDH1A1KDM4EHPGDKMT2ALMNA | |
| SCHEMBL28935071 | 0.79 | TUBB4A (0.41) | ALDH1A1KDM4ERAB9AHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804414-A4 | COMPLEMENTARY DNA AND TOXINS | SLOAN KETTERING INST CANCER (US) | 2000-04-12 | — | — | EP | disclosed |
| EP-0804414-A1 | COMPLEMENTARY DNA AND TOXINS | Sloan-Kettering Institute For Cancer Research (US) | 1997-11-05 | — | — | EP | disclosed |
| US-5652350-A | Complementary DNA and toxins | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1997-07-29 | — | — | US | disclosed |
| US-5571937-A | VIRICIDES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1996-11-05 | — | — | US | disclosed |
| WO-1995031434-A1 | COMPLEMENTARY DNA AND TOXINS | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1995-11-23 | — | — | WO | disclosed |