Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | GLA | P06280 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.43 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28239226 | 0.82 | ALDH1A1 (0.36) | ALDH1A1KDM4ERAB9AKMT2AHPGD | |
| SCHEMBL3203462 | 0.81 | ALDH1A1 (0.41) | ALDH1A1KDM4ERAB9AKMT2AHPGD | |
| SCHEMBL8000376 | 0.80 | ALDH1A1 (0.47) | ALDH1A1KDM4EGLARAB9AKMT2A | |
| SCHEMBL222907 | 0.79 | ALDH1A1 (0.50) | ALDH1A1KDM4EGLARAB9AKMT2A | |
| Water SCHEMBL7769205 | 0.78 | ALDH1A1 (0.49) | ALDH1A1KDM4EGLARAB9AKMT2A | |
| SCHEMBL3252424 | 0.77 | ALDH1A1 (0.45) | ALDH1A1KDM4EGLARAB9AKMT2A | |
| SCHEMBL3482953 | 0.76 | ALDH1A1 (0.44) | ALDH1A1KDM4EGLARAB9AKMT2A | |
| SCHEMBL28643462 | 0.74 | HTR6 (0.46) | ALDH1A1KDM4EGLARAB9AKMT2A | |
| SCHEMBL5192732 | 0.73 | KMT2A (0.58) | ALDH1A1KDM4EGLARAB9AKMT2A | |
| SCHEMBL7094916 | 0.73 | GAA (0.54) | ALDH1A1KDM4EGLARAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7824928-B2 | Hydrophilic chemiluminescent acridinium labeling reagents | QUEST DIAGNOSTICS INVESTMENTS INCORPORATED (US) | 2010-11-02 | — | — | US | disclosed |
| US-20080199973-A1 | HYDROPHILIC CHEMILUMINESCENT ACRIDINIUM LABELING REAGENTS | QUEST DIAGNOSTICS INVESTMENTS INCORPORATED | 2008-08-21 | — | — | US | disclosed |
| US-7297555-B2 | Hydrophilic chemiluminescent acridinium labeling reagents | QUEST DIAGNOSTICS INVESTMENTS INCORPORATED (US) | 2007-11-20 | — | — | US | disclosed |
| US-20050255528-A1 | Hydrophilic chemiluminescent acridinium labeling reagents | QUEST DIAGNOSTICS INVESTMENTS INCORPORATED | 2005-11-17 | — | — | US | disclosed |
| EP-1539702-A4 | HYDROPHILIC CHEMILUMINESCENT ACRIDINIUM LABELING REAGENTS | QUEST DIAGNOSTICS INVEST INC (US) | 2005-09-07 | — | — | EP | disclosed |
| US-6924154-B2 | Hydrophilic chemilumescent acridinium labeling reagents | QUEST DIAGNOSTICS INVESTMENTS INCORPORATED (US) | 2005-08-02 | — | — | US | disclosed |
| EP-1539702-A2 | HYDROPHILIC CHEMILUMINESCENT ACRIDINIUM LABELING REAGENTS | Quest Diagnostics Investments Incorporated (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004018418-A2 | HYDROPHILIC CHEMILUMINESCENT ACRIDINIUM LABELING REAGENTS | QUEST DIAGNOSTICS INVESTMENTS INCORPORATED (US) | 2004-03-04 | — | — | WO | disclosed |
| US-20040038294-A1 | Comprises hydrophilic sulfoalkyl substituents/linkers which offset hydrophobicity of acridinium ring system; improved attachment with antibody/handling | QUEST DIAGNOSTIC INVESTMENTS INCORPORATED | 2004-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080199973-A1 | HYDROPHILIC CHEMILUMINESCENT ACRIDINIUM LABELING REAGENTS | CTH, CBS, AHCY | ALDH1A1 1709/4885KDM4E 4666/4885GLA 2718/4885 |
| US-20050255528-A1 | Hydrophilic chemiluminescent acridinium labeling reagents | CTH, CBS, AHCY | ALDH1A1 1709/4885KDM4E 4666/4885GLA 2718/4885 |
| US-20040038294-A1 | Comprises hydrophilic sulfoalkyl substituents/linkers which offset hydrophobicity of acridinium ring system; improved attachment with antibody/handling | CTH, CBS, TST | ALDH1A1 2567/4885KDM4E 4312/4885GLA 3997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.