Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.49 |
| ▸ | CASP1 | P29466 | 3/20 | 0.49 |
| ▸ | CASP7 | P55210 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | RECQL | P46063 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | CASP6 | P55212 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | NSD2 | O96028 | 2/20 | 0.47 |
| ▸ | APEX1 | P27695 | 2/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8430986 | 0.89 | RAPGEF4 (0.49) | RAPGEF4ALDH1A1TDP1HSD17B10CASP1 | |
| SCHEMBL27509312 | 0.88 | RAPGEF4 (0.50) | RAPGEF4ALDH1A1TDP1HSD17B10CASP1 | |
| SCHEMBL3059008 | 0.86 | ALDH1A1 (0.61) | RAPGEF4ALDH1A1TDP1HSD17B10CASP1 | |
| SCHEMBL1373524 | 0.86 | ALDH1A1 (0.61) | RAPGEF4ALDH1A1TDP1HSD17B10CASP1 | |
| Water SCHEMBL28296857 | 0.86 | RAPGEF4 (0.49) | RAPGEF4ALDH1A1TDP1HSD17B10CASP1 | |
| SCHEMBL7787675 | 0.86 | MAPT (0.51) | RAPGEF4ALDH1A1TDP1HSD17B10CASP1 | |
| SCHEMBL21834461 | 0.85 | ALDH1A1 (0.59) | RAPGEF4ALDH1A1TDP1HSD17B10CASP1 | |
| SCHEMBL5185434 | 0.82 | RAPGEF4 (0.49) | RAPGEF4ALDH1A1TDP1HSD17B10CASP1 | |
| SCHEMBL29105091 | 0.82 | RAPGEF4 (0.45) | RAPGEF4ALDH1A1TDP1HSD17B10CASP1 | |
| SCHEMBL7511717 | 0.79 | RAPGEF4 (0.56) | RAPGEF4ALDH1A1TDP1HSD17B10CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023168-A4 | FIBER-REINFORCED PHTHALONITRILE COMPOSITE CURED WITH LOW-REACTIVITY AROMATIC AMINE CURING AGENT | US NAVY (US) | 2000-12-20 | — | — | EP | disclosed |
| EP-1023168-A1 | FIBER-REINFORCED PHTHALONITRILE COMPOSITE CURED WITH LOW-REACTIVITY AROMATIC AMINE CURING AGENT | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY OF THE NAVY (US) | 2000-08-02 | — | — | EP | disclosed |
| WO-1999017928-A1 | FIBER-REINFORCED PHTHALONITRILE COMPOSITE CURED WITH LOW-REACTIVITY AROMATIC AMINE CURING AGENT | THE GOVERNMENT OF THE UNITED STATES, REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1999-04-15 | — | — | WO | disclosed |