SCHEMBL7787675

SCHEMBL7787675

Nc1ccc(C(=O)c2ccccc2)c(S(=O)(=O)O)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.51
ALDH1A1 P00352 5/20 0.51
GAA P10253 3/20 0.51
POLB P06746 2/20 0.51
TDP1 Q9NUW8 2/20 0.51
KDM4E B2RXH2 2/20 0.51
NSD2 O96028 1/20 0.51
APEX1 P27695 1/20 0.51
APOBEC3A P31941 1/20 0.51
RECQL P46063 1/20 0.51
CASP6 P55212 1/20 0.51
APOBEC3G Q9HC16 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
PBRM1 Q86U86 1/20 0.50
KMT2A Q03164 4/20 0.49
LMNA P02545 3/20 0.49
HSD17B10 Q99714 2/20 0.45
CASP1 P29466 1/20 0.45
CASP7 P55210 1/20 0.45
MEN1 O00255 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8430986 0.90 RAPGEF4 (0.49) MAPTALDH1A1GAAPOLBTDP1
SCHEMBL8000414 0.86 RAPGEF4 (0.50) MAPTALDH1A1GAAPOLBTDP1
SCHEMBL7792233 0.82 KMT2A (0.62) MAPTALDH1A1GAAPOLBTDP1
SCHEMBL1373524 0.81 ALDH1A1 (0.61) MAPTALDH1A1GAAPOLBTDP1
SCHEMBL3059008 0.81 ALDH1A1 (0.61) MAPTALDH1A1GAAPOLBTDP1
SCHEMBL7788631 0.81 ALDH1A1 (0.49) MAPTALDH1A1KDM4EKMT2ALMNA
SCHEMBL21834461 0.80 ALDH1A1 (0.59) MAPTALDH1A1GAAPOLBTDP1
SCHEMBL300439 0.79 AKR1C3 (0.55) MAPTALDH1A1GAATDP1KDM4E
SCHEMBL27509312 0.79 RAPGEF4 (0.50) MAPTALDH1A1GAAPOLBTDP1
SCHEMBL29496654 0.78 AKR1C3 (0.53) MAPTALDH1A1GAATDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220226216-A1 HAIR TREATMENT METHOD KAO CORPORATION (JP) 2022-07-21 US disclosed
EP-3998060-A1 HAIR COSMETIC Kao Corporation (JP) 2022-05-18 EP disclosed
US-11234916-B2 Hair cosmetic KAO CORPORATION (JP) 2022-02-01 US disclosed
EP-3395323-B1 METHOD FOR TREATING HAIR KAO CORP (JP) 2021-09-29 EP disclosed
US-20210069081-A1 HAIR COSMETIC KAO CORPORATION (JP) 2021-03-11 US disclosed
EP-3741352-A1 HAIR COSMETIC COMPOSITION Kao Corporation (JP) 2020-11-25 EP disclosed
US-20190038532-A1 METHOD FOR TREATING HAIR KAO CORPORATION (JP) 2019-02-07 US disclosed
EP-3395323-A1 HAIR TREATMENT METHOD Kao Corporation (JP) 2018-10-31 EP disclosed
EP-0672405-B1 Hair treatment composition KAO CORP (JP) 2001-11-14 EP disclosed
EP-0743847-B1 HAIR COSMETIC COMPOSITION KAO CORP (JP) 2001-05-30 EP disclosed
US-6217855-B1 ELASTICITY KAO CORPORATION (JP) 2001-04-17 US disclosed
US-5683685-A NAPHTHALENESULFONIC ACID AND/OR BENZOPHENONE SULFONIC ACID WITH ANIONIC AND/OR AMPHOTERIC SURFACTANT WITH OIL KAO CORPORATION (JP) 1997-11-04 US disclosed
EP-0743847-A1 HAIR COSMETIC COMPOSITION Kao Corporation (JP) 1996-11-27 EP disclosed
EP-0529437-B1 Hair treatment composition KAO CORP (JP) 1996-07-17 EP disclosed
EP-0672405-A1 Hair treatment composition KAO CORPORATION (JP) 1995-09-20 EP disclosed
WO-1995020375-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 1995-08-03 WO disclosed
EP-0529437-A1 Hair treatment composition Kao Corporation (JP) 1993-03-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210069081-A1 HAIR COSMETIC TYR, CUTA, H1-0 MAPT 2404/4885ALDH1A1 494/4885GAA 1978/4885
US-20220226216-A1 HAIR TREATMENT METHOD POLR1C, ALDH7A1, CA7 MAPT 2556/4885ALDH1A1 6/4885GAA 2027/4885
US-20190038532-A1 METHOD FOR TREATING HAIR TYR, POLR1C, CA7 MAPT 1450/4885ALDH1A1 201/4885GAA 2602/4885
US-11234916-B2 Hair cosmetic TYR, CUTA, H1-0 MAPT 2404/4885ALDH1A1 494/4885GAA 1978/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.