Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 20/20 | 0.84 |
| ▸ | MMP13 | P45452 | 20/20 | 0.84 |
| ▸ | MMP1 | P03956 | 19/20 | 0.84 |
| ▸ | ADAM17 | P78536 | 16/20 | 0.84 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.69 |
| ▸ | MMP2 | P08253 | 1/20 | 0.69 |
| ▸ | MMP3 | P08254 | 1/20 | 0.69 |
| ▸ | MMP7 | P09237 | 1/20 | 0.69 |
| ▸ | MMP8 | P22894 | 1/20 | 0.69 |
| ▸ | MMP14 | P50281 | 1/20 | 0.69 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7410606 | 0.91 | MMP9 (1.00) | MMP9MMP13MMP1ADAM17 | |
| SCHEMBL7406630 | 0.91 | MMP9 (0.70) | MMP9MMP13MMP1ADAM17ADAMTS4 | |
| SCHEMBL6565576 | 0.91 | MMP9 (1.00) | MMP9MMP13MMP1ADAM17ADAMTS4 | |
| SCHEMBL7410569 | 0.88 | MMP1 (0.66) | MMP9MMP13MMP1ADAM17 | |
| SCHEMBL6567132 | 0.85 | MMP9 (1.00) | MMP9MMP13MMP1ADAM17 | |
| SCHEMBL6565402 | 0.85 | MMP9 (1.00) | MMP9MMP13MMP1ADAM17 | |
| SCHEMBL7404116 | 0.84 | MMP13 (1.00) | MMP9MMP13MMP1ADAM17MMP2 | |
| SCHEMBL7987992 | 0.84 | MMP9 (0.85) | MMP9MMP13MMP1ADAM17 | |
| SCHEMBL6568307 | 0.84 | MMP9 (1.00) | MMP9MMP13MMP1ADAM17 | |
| SCHEMBL7409556 | 0.83 | MMP9 (0.82) | MMP9MMP13MMP1ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288086-B1 | COMPOUNDS SUCH AS 1-METHYL-4-(4-BUTOXY-BENZENESULFONYL) -PIPERIDINE-4-CARBOXYLIC ACID HYDROXYAMIDE USED TO TREAT ARTHRITIS, TUMOR METASTASIS, TISSUE ULCERATION, ABNORMAL WOUND HEALING, ETC.; LOW MOLECULAR WEIGHT AND NON-PEPTIDAL | AMERICAN CYANAMID COMPANY | 2001-09-11 | — | — | US | disclosed |