Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.46 |
| ▸ | PPARG | P37231 | 6/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP7 | P09237 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP14 | P50281 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22864844 | 0.83 | PPARG (0.47) | PPARAPPARGMMP2MMP7MMP9 | |
| SCHEMBL5502208 | 0.80 | PPARA (0.48) | PPARAPPARGMMP2MMP7MMP9 | |
| SCHEMBL2686526 | 0.80 | SLC6A4 (0.59) | — | |
| SCHEMBL7987728 | 0.79 | TAAR1 (0.43) | — | |
| SCHEMBL3838706 | 0.78 | STS (0.63) | PPARAPPARGMMP2MMP7MMP9 | |
| SCHEMBL575589 | 0.77 | CA2 (0.52) | MMP2MMP7MMP9MMP14MMP1 | |
| SCHEMBL21349987 | 0.76 | KDM4E (0.50) | PPARAPPARGMMP2MMP7MMP9 | |
| SCHEMBL28939020 | 0.75 | STS (0.44) | PPARAPPARGMMP2MMP7MMP9 | |
| SCHEMBL6510217 | 0.75 | STS (0.44) | PPARAPPARGMMP2MMP7MMP9 | |
| SCHEMBL2000362 | 0.75 | STS (0.44) | PPARAPPARGMMP2MMP7MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288096-B1 | ANTIDIABETIC AGENTS, HYPOTENSIVE AGENTS, AND ANTICHOLESTEROL AGENTS | ASTRAZENECA AB (SE) | 2001-09-11 | — | — | US | disclosed |