Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanethidine SCHEMBL34754 | 1.00 | LMNA (1.00) | LMNAL3MBTL1HRH3ALDH1A1TSHR | |
| Sulfuric Acid SCHEMBL11726252 | 0.90 | LMNA (0.81) | LMNAL3MBTL1HRH3ALDH1A1TSHR | |
| Guanethidine SCHEMBL11658850 | 0.90 | LMNA (0.81) | LMNAL3MBTL1HRH3ALDH1A1TSHR | |
| Guanethidine SCHEMBL4332009 | 0.90 | LMNA (0.81) | LMNAL3MBTL1HRH3ALDH1A1TSHR | |
| Sulfuric Acid SCHEMBL11365481 | 0.88 | LMNA (0.78) | LMNAL3MBTL1HRH3ALDH1A1TSHR | |
| SCHEMBL2486864 | 0.87 | LMNA (0.77) | LMNAL3MBTL1HRH3ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL3667165 | 0.86 | LMNA (0.75) | LMNAHRH3CYP1A2 | |
| SCHEMBL2490640 | 0.84 | LMNA (0.73) | LMNAL3MBTL1HRH3ALDH1A1TSHR | |
| SCHEMBL6681216 | 0.83 | LMNA (0.70) | LMNAL3MBTL1HRH3ALDH1A1TSHR | |
| SCHEMBL8120185 | 0.83 | LMNA (0.70) | LMNAHRH3CYP1A2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000009115-A1 | GRP RECEPTOR LIGANDS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-24 | — | — | WO | disclosed |