Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Ethyl Tetradecanoate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | PAM | P19021 | 2/20 | 0.49 |
| ▸ | DGKA | P23743 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.45 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17961063 | 0.94 | DGKA (0.55) | MAPTPAMDGKALMNAKDM4E | |
| SCHEMBL30732583 | 0.92 | DGKA (0.53) | MAPTPAMDGKALMNAKDM4E | |
| Lactic Acid SCHEMBL28661413 | 0.91 | MAPT (0.64) | MAPTPAMDGKALMNAKDM4E | |
| Lactic Acid SCHEMBL29127009 | 0.89 | MAPT (0.61) | MAPTPAMDGKALMNAKDM4E | |
| SCHEMBL18000928 | 0.88 | PAM (0.49) | MAPTPAMDGKALMNAKDM4E | |
| Ethyl Tetradecanoate SCHEMBL29418166 | 0.88 | CA2 (0.58) | MAPTPAMDGKALMNAKDM4E | |
| SCHEMBL31239221 | 0.88 | CA2 (0.58) | MAPTPAMDGKALMNAKDM4E | |
| SCHEMBL29833581 | 0.88 | CA2 (0.58) | MAPTPAMDGKALMNAKDM4E | |
| SCHEMBL8163843 | 0.88 | CA2 (0.58) | MAPTPAMDGKALMNAKDM4E | |
| SCHEMBL31231845 | 0.88 | CA2 (0.58) | MAPTPAMDGKALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1011609-A4 | COMPOSITIONS FOR COSMETIC APPLICATIONS | MEDLOGIC GLOBAL CORP (US) | 2000-08-16 | — | — | EP | disclosed |
| EP-1011609-A1 | COMPOSITIONS FOR COSMETIC APPLICATIONS | MedLogic Global Corporation (US) | 2000-06-28 | — | — | EP | disclosed |
| WO-1998050005-A1 | COMPOSITIONS FOR COSMETIC APPLICATIONS | MEDLOGIC GLOBAL CORPORATION (US) | 1998-11-12 | — | — | WO | disclosed |