Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 7/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7227692 | 0.86 | HAO1 (0.40) | HAO1ALOX5 | |
| SCHEMBL25175773 | 0.83 | FFAR1 (0.42) | HAO1ALOX5 | |
| SCHEMBL8537191 | 0.81 | BACE1 (0.42) | — | |
| SCHEMBL28574194 | 0.81 | FABP7 (0.40) | HAO1 | |
| SCHEMBL25170006 | 0.77 | HAO1 (0.37) | HAO1ALOX5 | |
| SCHEMBL704145 | 0.74 | CA4 (0.37) | — | |
| SCHEMBL7092637 | 0.74 | CYP3A4 (0.42) | — | |
| SCHEMBL8135354 | 0.73 | — | — | |
| SCHEMBL4470099 | 0.73 | MAOB (0.42) | — | |
| SCHEMBL31637439 | 0.73 | MAOB (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001077114-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-10-18 | — | — | WO | disclosed |