Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 14/20 | 0.46 |
| ▸ | MMP9 | P14780 | 17/20 | 0.44 |
| ▸ | MMP13 | P45452 | 5/20 | 0.44 |
| ▸ | MMP14 | P50281 | 5/20 | 0.44 |
| ▸ | MMP1 | P03956 | 8/20 | 0.44 |
| ▸ | MMP3 | P08254 | 4/20 | 0.43 |
| ▸ | MMP8 | P22894 | 4/20 | 0.43 |
| ▸ | MMP7 | P09237 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8001199 | 1.00 | MMP2 (0.46) | MMP2MMP9MMP13MMP14MMP1 | |
| SCHEMBL8002270 | 0.80 | MMP9 (0.62) | MMP2MMP9MMP13MMP1MMP3 | |
| SCHEMBL8001198 | 0.80 | MMP9 (0.62) | MMP2MMP9MMP13MMP1MMP3 | |
| SCHEMBL7583731 | 0.79 | MMP9 (0.45) | MMP2MMP9MMP13MMP14MMP1 | |
| SCHEMBL8000592 | 0.75 | MMP9 (0.52) | MMP2MMP9MMP13MMP14MMP1 | |
| SCHEMBL8005101 | 0.74 | MMP9 (0.47) | MMP2MMP9MMP13MMP14MMP1 | |
| SCHEMBL7598899 | 0.74 | MMP9 (0.66) | MMP2MMP9MMP13MMP14MMP1 | |
| SCHEMBL7990004 | 0.74 | EPHX2 (0.48) | MMP2MMP9MMP13MMP14MMP1 | |
| SCHEMBL7999031 | 0.74 | MMP9 (0.66) | MMP2MMP9MMP13MMP14MMP1 | |
| SCHEMBL7535752 | 0.73 | MMP9 (0.43) | MMP2MMP9MMP13MMP14MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294573-B1 | FOR THERAPY RHEUMATOID ARTHRITIS, OSTEOARTHRITIS, OSTEOPENIAS SUCH AS OSTEOPOROSIS, PERIODONTITIS, GINGIVITIS, CORNEAL, EPIDERMAL OR GASTRIC ULCERATION, AND TUMOR GROWTH AND METASTASIS OR INVASION | ABBOTT LABORATORIES | 2001-09-25 | — | — | US | disclosed |