Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7999286 | 0.91 | MMP1 (0.39) | HPGDLMNACYP1A2PGRSLC6A2 | |
| SCHEMBL23839109 | 0.87 | GAA (0.44) | HPGDLMNACYP1A2ALDH1A1PGR | |
| SCHEMBL93302 | 0.84 | HPGD (0.54) | HPGDLMNACYP1A2ALDH1A1PGR | |
| SCHEMBL8002380 | 0.81 | LMNA (0.44) | HPGDLMNACYP1A2ALDH1A1PGR | |
| SCHEMBL6854428 | 0.81 | MEN1 (0.58) | HPGDLMNACYP1A2ALDH1A1PGR | |
| SCHEMBL27618708 | 0.79 | LMNA (0.53) | HPGDLMNACYP1A2ALDH1A1PGR | |
| SCHEMBL8649545 | 0.78 | LMNA (0.45) | HPGDLMNACYP1A2ALDH1A1PGR | |
| SCHEMBL5276524 | 0.77 | CA12 (0.44) | AKR1B1 | |
| SCHEMBL226212 | 0.76 | NPC1 (0.35) | HPGDLMNACYP1A2ALDH1A1GAA | |
| SCHEMBL93361 | 0.75 | LMNA (0.51) | HPGDLMNACYP1A2ALDH1A1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170038605-A1 | OPHTHALMIC EYEWEAR FOR REGULATING OCULAR EXPOSURE TO HIGH ENERGY ELECTROMAGNETIC RADIATION | JEROME LEGERTON A (US) | 2017-02-09 | — | — | US | disclosed |
| EP-0972223-A4 | LIGHT FILTERING CONTACT LENS | PARAGON VISION SCIENCES INC (US) | 2000-07-19 | — | — | EP | disclosed |
| EP-0972223-A1 | LIGHT FILTERING CONTACT LENS | PARAGON VISION SCIENCES, INC. (US) | 2000-01-19 | — | — | EP | disclosed |
| US-5846457-A | Light filtering contact lens method | SPORTSIGHT, LLC | 1998-12-08 | — | — | US | disclosed |
| WO-1998044380-A1 | LIGHT FILTERING CONTACT LENS | PARAGON VISION SCIENCES, INC. (US) | 1998-10-08 | — | — | WO | disclosed |
| US-5617154-A | Light filtering contact lens | FLEXLENS (US) | 1997-04-01 | — | — | US | disclosed |