Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 8/20 | 0.57 |
| ▸ | MMP9 | P14780 | 7/20 | 0.57 |
| ▸ | MMP8 | P22894 | 6/20 | 0.57 |
| ▸ | MMP3 | P08254 | 6/20 | 0.55 |
| ▸ | MMP1 | P03956 | 6/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | CTRC | Q99895 | 1/20 | 0.43 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.43 |
| ▸ | MMP13 | P45452 | 2/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7074188 | 0.93 | MMP2 (0.52) | MMP2MMP9MMP8MMP3MMP1 | |
| SCHEMBL7073432 | 0.91 | MMP2 (0.60) | MMP2MMP9MMP8MMP3MMP1 | |
| SCHEMBL7080932 | 0.88 | MMP2 (0.57) | MMP2MMP9MMP8MMP3MMP1 | |
| SCHEMBL8013554 | 0.88 | MMP2 (0.74) | MMP2MMP9MMP8MMP3MMP1 | |
| SCHEMBL7077830 | 0.85 | MMP2 (0.69) | MMP2MMP9MMP8MMP3MMP1 | |
| SCHEMBL7079276 | 0.84 | MMP2 (0.52) | MMP2MMP9MMP8MMP3MMP1 | |
| SCHEMBL7297379 | 0.78 | MMP13 (0.53) | MMP2MMP9MMP8MMP3MMP1 | |
| SCHEMBL7079905 | 0.78 | MMP2 (0.59) | MMP2MMP9MMP8MMP3MMP1 | |
| SCHEMBL6379618 | 0.77 | MMP2 (0.50) | MMP2MMP9MMP8MMP3MMP1 | |
| SCHEMBL7422537 | 0.76 | MMP2 (0.56) | MMP2MMP9MMP8MMP3MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6118001-A | ANTICANCER AGENT; ANTIARTHRITIC AGENT | DARWIN DISCOVERY, LTD. (GB) | 2000-09-12 | — | — | US | disclosed |