Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Octadecanoic Acid Amide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.48 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 4/20 | 0.40 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL271819 | 0.86 | TSHR (0.50) | CES2CES1TSHRMEN1ALDH1A1 | |
| Nonanoamide SCHEMBL27583769 | 0.86 | CES2 (0.62) | CES2CES1NAAATP53TSHR | |
| Benzoic Acid SCHEMBL28678293 | 0.84 | CES2 (0.61) | CES2CES1NAAATP53TSHR | |
| Benzoic Acid SCHEMBL17799552 | 0.80 | CES2 (0.59) | CES2CES1NAAATP53TSHR | |
| Octadecanoic Acid Amide SCHEMBL31472279 | 0.80 | TP53 (0.59) | TP53TSHRRARBPLA2G4BMEN1 | |
| Octadecanoic Acid Amide SCHEMBL8002943 | 0.80 | CES2 (0.46) | CES2CES1NAAAKDM4ESOAT1 | |
| Benzoic Acid SCHEMBL271750 | 0.79 | TSHR (0.42) | CES2CES1TSHRMEN1ALDH1A1 | |
| Isophthalic Acid SCHEMBL10888503 | 0.78 | LTB4R (0.43) | CES2CES1PLA2G4BMEN1KMT2A | |
| Terephthalic Acid SCHEMBL27926620 | 0.78 | TP53 (0.57) | TP53TSHRRARBPLA2G4BMEN1 | |
| Oleamide SCHEMBL4833055 | 0.78 | SOAT1 (0.68) | TP53MEN1MAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1011609-A4 | COMPOSITIONS FOR COSMETIC APPLICATIONS | MEDLOGIC GLOBAL CORP (US) | 2000-08-16 | — | — | EP | disclosed |
| EP-1011609-A1 | COMPOSITIONS FOR COSMETIC APPLICATIONS | MedLogic Global Corporation (US) | 2000-06-28 | — | — | EP | disclosed |
| WO-1998050005-A1 | COMPOSITIONS FOR COSMETIC APPLICATIONS | MEDLOGIC GLOBAL CORPORATION (US) | 1998-11-12 | — | — | WO | disclosed |