Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.41 |
| ▸ | TTPA | P49638 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8003203 | 0.85 | MAPT (0.64) | MAPTMEN1KMT2ATDP1PPARG | |
| SCHEMBL7986932 | 0.84 | MAPT (0.61) | MAPTMEN1KMT2ATDP1PPARG | |
| SCHEMBL8620604 | 0.81 | KMT2A (0.50) | MAPTMEN1KMT2ATDP1PPARG | |
| SCHEMBL9632107 | 0.81 | MAPT (0.60) | MAPTMEN1KMT2ATDP1PPARG | |
| SCHEMBL9559157 | 0.80 | MAPT (0.47) | MAPTMEN1KMT2ATDP1PPARG | |
| SCHEMBL8615056 | 0.80 | MAPT (0.48) | MAPTMEN1KMT2ATDP1PPARG | |
| SCHEMBL7492850 | 0.80 | MAPT (0.59) | MAPTMEN1KMT2ATDP1PPARG | |
| Hydrochloric Acid SCHEMBL9075198 | 0.80 | MAPT (0.47) | MAPTMEN1KMT2ATDP1PPARG | |
| Iodide SCHEMBL9223622 | 0.80 | MAPT (0.47) | MAPTMEN1KMT2ATDP1PPARG | |
| SCHEMBL8173098 | 0.79 | MEN1 (0.50) | MAPTMEN1KMT2ATDP1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5747528-A | Chroman derivatives as anti-oxidants | WARNER-LAMBERT COMPANY (US) | 1998-05-05 | — | — | US | disclosed |