SCHEMBL80034

SCHEMBL80034

Nc1ccc(Br)c(Br)c1Br

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AXL P30530 1/20 0.38
ALDH1A1 P00352 4/20 0.37
MAPT P10636 4/20 0.37
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
IMPDH2 P12268 1/20 0.37
POLB P06746 1/20 0.37
HTT P42858 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA4 P22748 1/20 0.36
CA6 P23280 1/20 0.36
CA5A P35218 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36
CA5B Q9Y2D0 1/20 0.36
APAF1 O14727 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29160600 0.97 ALDH1A1 (0.39) AXLALDH1A1MAPTMEN1KMT2A
SCHEMBL22366550 0.87 IMPDH2 (0.42) AXLALDH1A1MAPTMEN1KMT2A
SCHEMBL11786172 0.80 ESR1 (0.36)
SCHEMBL29646281 0.79 CYP2A6 (0.39) ALDH1A1CA1CA2CA4CA6
SCHEMBL358557 0.79 CYP2A6 (0.39) ALDH1A1CA1CA2CA4CA6
SCHEMBL241304 0.79 AXL (0.37) AXLALDH1A1MAPTMEN1KMT2A
SCHEMBL30555943 0.75 CYP2A6 (0.36) ALDH1A1TDP1ALOX15
Methane SCHEMBL28608338 0.75 CYP2A6 (0.36) ALDH1A1TDP1ALOX15
SCHEMBL27534281 0.75 CYP2A6 (0.36) ALDH1A1TDP1ALOX15
SCHEMBL30555886 0.75 CYP2A6 (0.36) ALDH1A1TDP1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 639 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119662039-A Bromine-containing disperse dye, preparation method and application thereof 宁夏宁泰科技有限公司 2025-03-21 CN claimed
CN-119639262-A Polymer waterproof coating, preparation method and use method thereof 北京圣洁防水材料有限公司 2025-03-18 CN claimed
CN-119029313-A High-rate stable nonaqueous electrolyte and lithium battery comprising same 江苏欧力特能源科技有限公司 2024-11-26 CN claimed
CN-118572161-A Anion exchange membrane of all-iron flow battery and preparation method and application thereof 中国科学院金属研究所 2024-08-30 CN claimed
CN-111072872-B Temperature-resistant flame-retardant epoxy vinyl ester resin and high-toughness temperature-resistant flame-retardant glass flake clay containing same 华东理工大学华昌聚合物有限公司 2023-07-04 CN claimed
EP-3282496-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2023-04-26 EP claimed
CN-114832799-B Preparation and application of carbon-point bonded silica gel chromatographic stationary phase based on eutectic solvent 中国科学院兰州化学物理研究所 2023-02-28 CN claimed
CN-113896822-B Preparation method of high-efficiency flame-retardant polystyrene by applying bromine flame retardant containing active functional group 江苏越升科技股份有限公司 2022-10-04 CN claimed
EP-3229284-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2022-08-31 EP claimed
CN-114832799-A Preparation and application of carbon-point bonded silica gel chromatographic stationary phase based on eutectic solvent 中国科学院兰州化学物理研究所 2022-08-02 CN claimed
US-20140249233-A1 METHOD FOR ENHANCING FOLDING AND TRANSPORT OF MISFOLDED GLUCOCEREBROSIDASE THE HOSPITAL FOR SICK CHILDREN (CA) 2014-09-04 US claimed
US-20140235713-A1 METHOD OF TREATING LYSOSOMAL STORAGE DISORDERS THE HOSPITAL FOR SICK CHILDREN (CA) 2014-08-21 US claimed
WO-2014099397-A1 FLAME RETARDANT POLYMER COMPOSITIONS POLYAD SERVICES LLC (US) 2014-06-26 WO claimed
WO-2012103238-A2 POLYIMIDE POLYMER FROM NON-STOICHIOMETRIC COMPONENTS NEXOLVE CORPORATIOIN (US) 2012-08-02 WO claimed
US-20120190802-A1 POLYIMIDE POLYMER FROM NON-STOICHIOMETRIC COMPONENTS NEXOLVE CORPORATION (US) 2012-07-26 US claimed
EP-0812824-B1 Process for preparing N-substituted maleimides DAIHACHI CHEM IND (JP) 2001-04-04 EP claimed
US-5741913-A REACTING MALEIC ANHYDRIDE WITH A PRIMARY AMINE IN MIXTURE OF PROTIC POLAR AND NONPOLAR SOLVENTS IN PRESENCE OF ACID CATALYST AND POLYMERIZATION INHIBITOR, EFFICIENCY DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 1998-04-21 US claimed
EP-0812824-A1 Process for preparing N-substituted maleimides DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 1997-12-17 EP claimed
EP-0322643-B1 MEDICINES CONTAINING AS A MIXTURE INTERFERON AND 1-DESOXY-PIPERIDINOSES, PROCESS FOR THEIR MANUFACTURE AND THEIR USE BAYER AG (DE) 1991-07-24 EP claimed
EP-0257753-A1 Novel derivatives of trihalopivalic acids, method for their preparation and their use Bromine Compounds Ltd. (IL) 1988-03-02 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140235713-A1 METHOD OF TREATING LYSOSOMAL STORAGE DISORDERS GAA, GBA1, GBA2 AXL 4784/4885ALDH1A1 2605/4885MAPT 841/4885
US-20140249233-A1 METHOD FOR ENHANCING FOLDING AND TRANSPORT OF MISFOLDED GLUCOCEREBROSIDASE GBA1, GBA3, GAA AXL 4869/4885ALDH1A1 2858/4885MAPT 595/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.