SCHEMBL241304

SCHEMBL241304

Nc1ccc(Br)c(Br)c1N

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AXL P30530 1/20 0.37
MAPT P10636 4/20 0.35
ALDH1A1 P00352 4/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
POLB P06746 1/20 0.35
HTT P42858 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
GAA P10253 1/20 0.35
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA4 P22748 1/20 0.34
CA6 P23280 1/20 0.34
CA5A P35218 1/20 0.34
CA7 P43166 1/20 0.34
CA9 Q16790 1/20 0.34
CA14 Q9ULX7 1/20 0.34
CA5B Q9Y2D0 1/20 0.34
APAF1 O14727 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11128863 0.81 MAPT (0.38) AXLMAPTALDH1A1MEN1KMT2A
SCHEMBL80034 0.79 AXL (0.38) AXLMAPTALDH1A1MEN1KMT2A
Hydrochloric Acid SCHEMBL29160600 0.77 ALDH1A1 (0.39) AXLMAPTALDH1A1MEN1KMT2A
SCHEMBL239457 0.72 PTGER4 (0.43) AXLMAPTALDH1A1MEN1KMT2A
SCHEMBL21980637 0.72 POLB (0.44) MAPTALDH1A1MEN1KMT2APOLB
SCHEMBL6960971 0.72 CA1 (0.40) AXLMAPTALDH1A1MEN1KMT2A
SCHEMBL7209297 0.72 TSHR (0.39) MAPTALDH1A1GAACA12CA1
SCHEMBL15231722 0.72 ALDH1A1 (0.39) ALDH1A1CA12CA1CA2CA4
SCHEMBL10736045 0.72 GAA (0.32) MAPTGAA
SCHEMBL145182 0.72 ALDH1A1 (0.39) AXLMAPTALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114573805-B Preparation method of high-barrier transparent flame-retardant copolymerized nylon 浙江恒逸石化研究院有限公司 2024-03-08 CN claimed
CN-114874418-B Conjugated polymer based on trifluoromethyl substituted quinoxaline, and preparation method and application thereof 广东聚石科技研究有限公司 2023-12-19 CN claimed
CN-114874418-A Conjugated polymer based on trifluoromethyl substituted quinoxaline and preparation method and application thereof 广东聚石科技研究有限公司 2022-08-09 CN claimed
CN-108440417-B 1- methyl thio phenyl benzimidazole and its derivative synthesizing process 湘潭大学 2019-09-24 CN claimed
CN-108440417-A 1- methyl thio phenyls benzimidazole and its derivative synthesizing process 湘潭大学 2018-08-24 CN claimed
CN-114573805-B Preparation method of high-barrier transparent flame-retardant copolymerized nylon 浙江恒逸石化研究院有限公司 2024-03-08 CN disclosed
CN-114874418-B Conjugated polymer based on trifluoromethyl substituted quinoxaline, and preparation method and application thereof 广东聚石科技研究有限公司 2023-12-19 CN disclosed
CN-114573796-B Tris (4-ethynylphenyl) amine conjugated microporous polymer, preparation method and application 郑州轻工业大学 2023-08-04 CN disclosed
US-11446294-B2 Non-platinum-based anti-cancer compounds for use in targeted chemotherapy LU QING BIN (CA) 2022-09-20 US disclosed
CN-114874418-A Conjugated polymer based on trifluoromethyl substituted quinoxaline and preparation method and application thereof 广东聚石科技研究有限公司 2022-08-09 CN disclosed
CN-114573796-A Tris (4-ethynylphenyl) amine conjugated microporous polymer, preparation method and application 郑州轻工业大学 2022-06-03 CN disclosed
CN-114380700-A Non-platinum based anti-cancer compounds for targeted chemotherapy 卢庆彬 2022-04-22 CN disclosed
CN-102276799-B Quinoxaline unit-containing fluorene copolymer, and preparation method and application thereof OCEANS KING LIGHTING TECH CO 2014-05-28 CN disclosed
US-20120101243-A1 SUBSTITUTED BENZAZOLOPORPHYRAZINES FOR POLYMERIZATION AND SURFACE ATTACHMENT AND ARTICLES FORMED THEREFROM UNITED STATES DEPARTMENT OF ENERGY 2012-04-26 US disclosed
US-8106393-B2 Substituted benzazoloporphyrazines for polymerization and surface attachment and articles formed therefrom NORTH CAROLINA STATE UNIVERSITY (US) 2012-01-31 US disclosed
US-20120004384-A1 SUBSTITUTED BENZAZOLOPORPHYRAZINES FOR POLYMERIZATION AND SURFACE ATTACHMENT AND ARTICLES FORMED THEREFROM UNITED STATES DEPARTMENT OF ENERGY 2012-01-05 US disclosed
US-7919770-B2 Substituted benzazoloporphyrazines for polymerization and surface attachment and articles formed therefrom NORTH CAROLINA STATE UNIVERSITY (US) 2011-04-05 US disclosed
CN-1891754-B Novel organic polymer semiconductor, method for forming organic polymer semiconductor thin film and organic thin film transistor using the same SAMSUNG ELECTRONICS CO LTD 2011-03-09 CN disclosed
US-20110015388-A1 Substituted benzazoloporphyrazines for polymerization and surface attachment and articles formed therefrom UNITED STATES DEPARTMENT OF ENERGY 2011-01-20 US disclosed
CN-1891754-A Novel organic polymer semiconductor, method for forming organic polymer semiconductor thin film and organic thin film transistor using the same SAMSUNG ELECTRONICS CO LTD (KR) 2007-01-10 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120004384-A1 SUBSTITUTED BENZAZOLOPORPHYRAZINES FOR POLYMERIZATION AND SURFACE ATTACHMENT AND ARTICLES FORMED THEREFROM PNMT, HNMT, COMT AXL 724/4885MAPT 971/4885ALDH1A1 767/4885
US-11446294-B2 Non-platinum-based anti-cancer compounds for use in targeted chemotherapy TOP2B, RB1, POLR2B AXL 2587/4885MAPT 3743/4885ALDH1A1 849/4885
US-20120101243-A1 SUBSTITUTED BENZAZOLOPORPHYRAZINES FOR POLYMERIZATION AND SURFACE ATTACHMENT AND ARTICLES FORMED THEREFROM PNMT, HNMT, COMT AXL 724/4885MAPT 971/4885ALDH1A1 767/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.