Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.37 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8003454 | 0.81 | IAPP (0.45) | IAPPALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL27620072 | 0.81 | L3MBTL1 (0.44) | CYP11B1CYP11B2ALDH1A1LMNATRIM24 | |
| SCHEMBL19460839 | 0.79 | KDM4E (0.46) | CYP11B1CYP11B2ALDH1A1LMNACYP1A2 | |
| SCHEMBL27938298 | 0.79 | CYP11B1 (0.44) | CYP11B1CYP11B2ALDH1A1TRIM24TRIM33 | |
| SCHEMBL30950077 | 0.79 | CYP11B1 (0.44) | CYP11B1CYP11B2ALDH1A1KMT2AMEN1 | |
| SCHEMBL555808 | 0.78 | MTNR1A (0.58) | KMT2AMEN1LMNACYP1A2CYP2C19 | |
| SCHEMBL5182214 | 0.77 | TAAR1 (0.47) | IAPPALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL28356661 | 0.76 | TDP1 (0.49) | CYP11B1CYP11B2ALDH1A1LMNAKDM4E | |
| SCHEMBL2184230 | 0.76 | LIPG (0.47) | CYP11B1CYP11B2KMT2AMEN1MAPT | |
| SCHEMBL11521698 | 0.76 | LIPG (0.47) | CYP11B1CYP11B2KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000008026-A2 | FUNGICIDAL FUSED BICYCLIC HETEROCYCLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-02-17 | — | — | WO | disclosed |