SCHEMBL80035

SCHEMBL80035

Brc1ccccc1N(Br)Br

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
MAPK1 P28482 1/20 0.36
BBOX1 O75936 1/20 0.35
EHMT2 Q96KQ7 1/20 0.35
EHMT1 Q9H9B1 1/20 0.35
ESR1 P03372 2/20 0.34
TAAR1 Q96RJ0 2/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
GAA P10253 1/20 0.32
IDO1 P14902 2/20 0.31
PLCG1 P19174 1/20 0.31
HTR7 P34969 2/20 0.30
TSHR P16473 1/20 0.30
MGLL Q99685 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28468266 0.95 ALDH1A1 (0.36) ALDH1A1MAPK1BBOX1EHMT2EHMT1
SCHEMBL28424135 0.90 ALDH1A1 (0.33) ALDH1A1MAPK1ESR1TAAR1
Sulfuric Acid SCHEMBL31468827 0.86 ESR1 (0.42) ALDH1A1ESR1CA1CA2CA4
SCHEMBL11786178 0.81 ESR1 (0.40) ALDH1A1ESR1TAAR1HTR7TSHR
SCHEMBL1874023 0.79 ALDH1A1 (0.41) ALDH1A1MAPK1BBOX1EHMT2EHMT1
SCHEMBL30631792 0.79 ALDH1A1 (0.41) ALDH1A1MAPK1BBOX1EHMT2EHMT1
SCHEMBL6675092 0.78 ALDH1A1 (0.31) ALDH1A1GAA
Hydrochloric Acid SCHEMBL28376010 0.77 ALDH1A1 (0.39) ALDH1A1MAPK1ESR1TAAR1CA1
SCHEMBL2213137 0.76 ESR1 (0.35) ALDH1A1MAPK1ESR1TAAR1CA1
SCHEMBL545805 0.74 ALDH1A1 (0.44) ALDH1A1MAPK1ESR1TAAR1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 620 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119662039-A Bromine-containing disperse dye, preparation method and application thereof 宁夏宁泰科技有限公司 2025-03-21 CN claimed
CN-119639262-A Polymer waterproof coating, preparation method and use method thereof 北京圣洁防水材料有限公司 2025-03-18 CN claimed
CN-119029313-A High-rate stable nonaqueous electrolyte and lithium battery comprising same 江苏欧力特能源科技有限公司 2024-11-26 CN claimed
CN-111072872-B Temperature-resistant flame-retardant epoxy vinyl ester resin and high-toughness temperature-resistant flame-retardant glass flake clay containing same 华东理工大学华昌聚合物有限公司 2023-07-04 CN claimed
EP-3282496-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2023-04-26 EP claimed
CN-114832799-B Preparation and application of carbon-point bonded silica gel chromatographic stationary phase based on eutectic solvent 中国科学院兰州化学物理研究所 2023-02-28 CN claimed
CN-113896822-B Preparation method of high-efficiency flame-retardant polystyrene by applying bromine flame retardant containing active functional group 江苏越升科技股份有限公司 2022-10-04 CN claimed
EP-3229284-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2022-08-31 EP claimed
CN-114832799-A Preparation and application of carbon-point bonded silica gel chromatographic stationary phase based on eutectic solvent 中国科学院兰州化学物理研究所 2022-08-02 CN claimed
CN-113896822-A Preparation method of high-efficiency flame-retardant polystyrene by applying bromine flame retardant containing active functional group 南京越升挤出机械有限公司 2022-01-07 CN claimed
US-20140235713-A1 METHOD OF TREATING LYSOSOMAL STORAGE DISORDERS THE HOSPITAL FOR SICK CHILDREN (CA) 2014-08-21 US claimed
WO-2014099397-A1 FLAME RETARDANT POLYMER COMPOSITIONS POLYAD SERVICES LLC (US) 2014-06-26 WO claimed
CN-103616798-A Photosensitive resin with flame retardant property and application thereof in production of photosensitive ink ZHANG GAOYUAN 2014-03-05 CN claimed
WO-2012103238-A2 POLYIMIDE POLYMER FROM NON-STOICHIOMETRIC COMPONENTS NEXOLVE CORPORATIOIN (US) 2012-08-02 WO claimed
US-20120190802-A1 POLYIMIDE POLYMER FROM NON-STOICHIOMETRIC COMPONENTS NEXOLVE CORPORATION (US) 2012-07-26 US claimed
EP-0812824-B1 Process for preparing N-substituted maleimides DAIHACHI CHEM IND (JP) 2001-04-04 EP claimed
US-5741913-A REACTING MALEIC ANHYDRIDE WITH A PRIMARY AMINE IN MIXTURE OF PROTIC POLAR AND NONPOLAR SOLVENTS IN PRESENCE OF ACID CATALYST AND POLYMERIZATION INHIBITOR, EFFICIENCY DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 1998-04-21 US claimed
EP-0812824-A1 Process for preparing N-substituted maleimides DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 1997-12-17 EP claimed
EP-0322643-B1 MEDICINES CONTAINING AS A MIXTURE INTERFERON AND 1-DESOXY-PIPERIDINOSES, PROCESS FOR THEIR MANUFACTURE AND THEIR USE BAYER AG (DE) 1991-07-24 EP claimed
EP-0257753-A1 Novel derivatives of trihalopivalic acids, method for their preparation and their use Bromine Compounds Ltd. (IL) 1988-03-02 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140235713-A1 METHOD OF TREATING LYSOSOMAL STORAGE DISORDERS GAA, GBA1, GBA2 ALDH1A1 2605/4885MAPK1 4265/4885BBOX1 605/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.