Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 2/20 | 0.34 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.33 |
| ▸ | GAA known ✓ | P10253 | 1/20 | 0.32 |
| ▸ | HTR2A known ✓ | P28223 | 2/20 | 0.32 |
| ▸ | HTR2C known ✓ | P28335 | 2/20 | 0.32 |
| ▸ | HTR2B known ✓ | P41595 | 2/20 | 0.32 |
| ▸ | HRH3 known ✓ | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | HTR7 known ✓ | P34969 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1874023 | 0.97 | ALDH1A1 (0.41) | ALDH1A1MAPK1IDO1ESR1TAAR1 | |
| SCHEMBL30631792 | 0.97 | ALDH1A1 (0.41) | ALDH1A1MAPK1IDO1ESR1TAAR1 | |
| SCHEMBL30282355 | 0.81 | ALDH1A1 (0.41) | ALDH1A1MAPK1ESR1TDP1TSHR | |
| SCHEMBL1168198 | 0.81 | ALDH1A1 (0.41) | ALDH1A1MAPK1ESR1TDP1TSHR | |
| SCHEMBL1330156 | 0.81 | ALDH1A1 (0.41) | ALDH1A1MAPK1ESR1TDP1TSHR | |
| SCHEMBL20186660 | 0.81 | ESR1 (0.35) | ALDH1A1MAPK1ESR1TAAR1CA1 | |
| Hydrochloric Acid SCHEMBL27838096 | 0.80 | ALDH1A1 (0.38) | ALDH1A1MAPK1IDO1ESR1TAAR1 | |
| SCHEMBL5730842 | 0.80 | ALDH1A1 (0.38) | ALDH1A1MAPK1IDO1ESR1TAAR1 | |
| SCHEMBL15377824 | 0.79 | ALDH1A1 (0.39) | ALDH1A1MAPK1ESR1TDP1TSHR | |
| Hydrochloric Acid SCHEMBL2872399 | 0.78 | MAPT (0.43) | ALDH1A1MAPK1ESR1TAAR1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108604643-B | Organic electroluminescent element | 保土谷化学工业株式会社 | 2022-02-15 | — | — | CN | claimed |
| CN-115210899-A | Organic electroluminescent element | 保土谷化学工业株式会社 | 2022-10-18 | — | — | CN | disclosed |
| CN-115003729-A | High molecular weight compound and light emitting diode containing the same | 保土谷化学工业株式会社 | 2022-09-02 | — | — | CN | disclosed |
| CN-114981991-A | Organic electroluminescent element | 保土谷化学工业株式会社 | 2022-08-30 | — | — | CN | disclosed |
| CN-114946273-A | Organic electroluminescent element | 保土谷化学工业株式会社 | 2022-08-26 | — | — | CN | disclosed |
| CN-114867713-A | Arylamine compound and organic electroluminescent element | 保土谷化学工业株式会社 | 2022-08-05 | — | — | CN | disclosed |
| CN-110431680-B | Organic electroluminescent element | 保土谷化学工业株式会社 | 2022-07-08 | — | — | CN | disclosed |
| CN-109844978-B | Indenocarbazole compound and organic electroluminescent element | 保土谷化学工业株式会社 | 2022-06-14 | — | — | CN | disclosed |
| CN-114586189-A | Organic electroluminescent element | 保土谷化学工业株式会社 | 2022-06-03 | — | — | CN | disclosed |
| CN-108604643-B | Organic electroluminescent element | 保土谷化学工业株式会社 | 2022-02-15 | — | — | CN | disclosed |
| CN-111869326-A | Organic electroluminescent element and method for manufacturing the same | 保土谷化学工业株式会社 | 2020-10-30 | — | — | CN | disclosed |
| CN-111567141-A | Organic EL element, amine compound having benzoxazole ring structure, and method for using same in capping layer of organic EL element | 保土谷化学工业株式会社 | 2020-08-21 | — | — | CN | disclosed |
| CN-111344879-A | Organic electroluminescent element | 保土谷化学工业株式会社 | 2020-06-26 | — | — | CN | disclosed |
| CN-111316462-A | Compound having indenocarbazole ring structure and organic electroluminescent element | 保土谷化学工业株式会社 | 2020-06-19 | — | — | CN | disclosed |
| CN-108369994-B | Organic electroluminescent element | 保土谷化学工业株式会社 | 2020-05-19 | — | — | CN | disclosed |
| CN-111164778-A | Organic electroluminescent element | 保土谷化学工业株式会社 | 2020-05-15 | — | — | CN | disclosed |
| CN-111095588-A | Organic electroluminescent element | 保土谷化学工业株式会社 | 2020-05-01 | — | — | CN | disclosed |
| CN-111094264-A | Compound having pyrimidine ring structure and organic electroluminescent element | 保土谷化学工业株式会社 | 2020-05-01 | — | — | CN | disclosed |
| CN-110998889-A | Organic electroluminescent element containing compound having benzoxazole ring structure | 保土谷化学工业株式会社 | 2020-04-10 | — | — | CN | disclosed |
| CN-110776515-A | Compound having azaindeno [1, 2, c ] phenanthrene ring structure and organic electroluminescent element using same | 保土谷化学工业株式会社 | 2020-02-11 | — | — | CN | disclosed |