Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | NEK2 | P51955 | 1/20 | 0.43 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29713864 | 1.00 | ALDH1A1 (0.44) | ALDH1A1MAPTGAATP53TSHR | |
| Hydrochloric Acid SCHEMBL2872399 | 0.97 | MAPT (0.43) | ALDH1A1MAPTGAATP53TSHR | |
| SCHEMBL10340767 | 0.97 | MAPT (0.43) | ALDH1A1MAPTGAATP53TSHR | |
| SCHEMBL1328337 | 0.83 | ALDH1A1 (0.43) | ALDH1A1MAPTGAATP53TSHR | |
| SCHEMBL27821582 | 0.81 | MEN1 (0.42) | ALDH1A1MAPTGAATP53TSHR | |
| SCHEMBL413186 | 0.80 | ALDH1A1 (0.44) | ALDH1A1MAPTGAATP53TSHR | |
| SCHEMBL4581592 | 0.79 | ALDH1A1 (0.40) | ALDH1A1MAPTGAATP53TSHR | |
| SCHEMBL12027990 | 0.79 | ALDH1A1 (0.40) | ALDH1A1MAPTGAATP53TSHR | |
| SCHEMBL30172472 | 0.79 | ALDH1A1 (0.40) | ALDH1A1MAPTGAATP53TSHR | |
| SCHEMBL9566860 | 0.79 | MAPT (0.46) | ALDH1A1MAPTGAATP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 378 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111278837-B | Hydrocarbon-soluble halogen and thiol/magnesium exchange reagent | 雅宝德国有限责任公司 | 2024-04-09 | — | — | CN | claimed |
| EP-3688000-B1 | HYDROCARBON-SOLUBLE HALOGEN AND THIOLATE/MAGNESIUM EXCHANGE REAGENTS | ALBEMARLE GERMANY GMBH (DE) | 2023-11-08 | — | — | EP | claimed |
| CN-113264844-B | Method for preparing aryl amide compound by catalyzing carbonylation of aryl tertiary amine without metal catalytic system | 宿州学院 | 2023-05-02 | — | — | CN | claimed |
| US-11236113-B2 | Hydrocarbon-soluble halogen and thiolate/magnesium exchange reagents | ALBEMARLE GERMANY GMBH (DE) | 2022-02-01 | — | — | US | claimed |
| CN-112920113-A | Beta amyloid-targeted fluorescent probe, preparation method thereof and application thereof in Alzheimer's disease | 华南理工大学 | 2021-06-08 | — | — | CN | claimed |
| US-20200239496-A1 | Hydrocarbon-Soluble Halogen and Thiolate/Magnesium Exchange Reagents | Ludwig-Maximilians-Universitat München (DE) | 2020-07-30 | — | — | US | claimed |
| CN-108586536-B | 2- [ (2-dimethylamino phenyl) (phenyl) phosphine ] -N, N-dimethylaniline cuprous iodide complex and synthetic method thereof | 湖北大学 | 2020-04-28 | — | — | CN | claimed |
| CN-110483581-A | It is a kind of containing the palladium complex of carborane ligand and its preparation and application between double phosphines | SHANGHAI INST TECH | 2019-11-22 | — | — | CN | claimed |
| CN-108690032-A | A kind of fluorescent dye and its synthetic method of azophenlyene fused structure | 湖南大学 | 2018-10-23 | — | — | CN | claimed |
| CN-108586536-A | 2- [(2- dimethylaminophenyls) (phenyl) phosphine]-N, N- dimethylaniline cuprous iodide complexs and synthetic method | 湖北大学 | 2018-09-28 | — | — | CN | claimed |
| EP-2027140-B1 | INDUSTRIAL PROCESS FOR THE SYNTHESIS OF 17 ALPHA -ACETOXY-11 BETA -[4-(N,N-DIMETHYL-AMINO)- PHENYL]-19-NORPREGNA-4,9-DIENE-3,20-DIONE AND NEW INTERMEDIATES OF THE PROCESS | RICHTER GEDEON NYRT (HU) | 2013-03-13 | — | — | EP | claimed |
| US-8110691-B2 | Industrial process for the synthesis of 17α-acetoxy-11β-[4-(N,N-dimethyl-amino)-phenyl]-19-norpregna-4,9-diene-3,20-dione and new intermediates of the process | RICHTER GEDEON NYRT. (HU) | 2012-02-07 | — | — | US | claimed |
| US-20090187032-A1 | INDUSTRIAL PROCESS FOR THE SYNTHESIS OF 17alpha-ACETOXY-11beta-[4-(N,N-DIMETHYL-AMINO)-PHENYL]-19-NORPREGNA-4,9-DIENE-3,20-DIONE AND NEW INTERMEDIATES OF THE PROCESS | RICHTER GEDEON NYRT. (HU) | 2009-07-23 | — | — | US | claimed |
| EP-2027140-A1 | INDUSTRIAL PROCESS FOR THE SYNTHESIS OF 17 ALPHA -ACETOXY-11 BETA -[4-(N,N-DIMETHYL-AMINO)- PHENYL]-19-NORPREGNA-4,9-DIENE-3,20-DIONE AND NEW INTERMEDIATES OF THE PROCESS | Richter Gedeon NYRT (HU) | 2009-02-25 | — | — | EP | claimed |
| WO-2007144674-A1 | INDUSTRIAL PROCESS FOR THE SYNTHESIS OF 17α-ACETOXY-11β-[4-(N,N-DIMETHYL-AMINO)- PHENYL]-19-NORPREGNA-4,9-DIENE-3,20-DIONE AND NEW INTERMEDIATES OF THE PROCESS | RICHTER GEDEON NYRT (HU) | 2007-12-21 | — | — | WO | claimed |
| EP-1613640-A2 | METHOD FOR PREPARING 17 ALPHA-ACETOXY-11 BETA-(4-N,N-DIMETHYLAMIN OPHENYL)-19-NORPREGNA-4,9-DIENE-3,20-DIONE, INTERMEDIATES THEREOF, AND METHODS FOR THE PREPARATION OF SUCH INTERMEDIATES | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2006-01-11 | — | — | EP | claimed |
| WO-2004078709-A2 | METHOD FOR PREPARING 17 α-ACETOXY-11β-(4-N,N-DIMETHYLAMINOPHENYL)-19-NORPREGNA-4,9-DIENE-3,20-DIONE, INTERMEDIATES THEREOF, AND METHODS FOR THE PREPARATION OF SUCH INTERMEDIATES | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2004-09-16 | — | — | WO | claimed |
| EP-0505890-B1 | Process for producing a styrenic polymer | IDEMITSU KOSAN CO (JP) | 1997-05-28 | — | — | EP | claimed |
| US-5576460-A | REACTING AM AMINE WITH AN AROMATIC COMPOUND USING A NICKEL OR PALLADIUM CATALYST | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1996-11-19 | — | — | US | claimed |
| US-4258123-A | UNSATURATED COMPOUND, HALOGENATED TRIAZINE, UNSATURATED KETONE | FUJI PHOTO FILM CO., LTD. (JP) | 1981-03-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200239496-A1 | Hydrocarbon-Soluble Halogen and Thiolate/Magnesium Exchange Reagents | OR10J3, MSRB3, SLC39A3 | ALDH1A1 2020/4885MAPT 2293/4885GAA 4782/4885 |
| US-20090187032-A1 | INDUSTRIAL PROCESS FOR THE SYNTHESIS OF 17alpha-ACETOXY-11beta-[4-(N,N-DIMETHYL-AMINO)-PHENYL]-19-NORPREGNA-4,9-DIENE-3,20-DIONE AND NEW INTERMEDIATES OF THE PROCESS | HSD17B11, HSD17B7, HSD17B13 | ALDH1A1 811/4885MAPT 4428/4885GAA 1208/4885 |
| US-11236113-B2 | Hydrocarbon-soluble halogen and thiolate/magnesium exchange reagents | MSRB3, OR10J3, GFER | ALDH1A1 2179/4885MAPT 2403/4885GAA 4811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.