Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALB | P02768 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | TK1 | P04183 | 5/20 | 0.37 |
| ▸ | TK2 | O00142 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6909597 | 0.90 | TK2 (0.38) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL7084531 | 0.89 | LMNA (0.40) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL7025003 | 0.87 | LMNA (0.39) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL6663227 | 0.85 | TK1 (0.39) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL28072298 | 0.76 | TK1 (0.43) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL27349255 | 0.76 | TK1 (0.42) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL18642515 | 0.75 | TK1 (0.46) | POLBTK1 | |
| SCHEMBL1825757 | 0.75 | TK1 (0.43) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL12658380 | 0.75 | TK1 (0.43) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL8904559 | 0.75 | TK1 (0.43) | LMNAALBBLMALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000008214-A1 | OLIGONUCLEOTIDE ANALOGS HAVING MODIFIED DIMERS | ISIS PHARMACEUTICALS, INC. (US) | 2000-02-17 | — | — | WO | disclosed |