Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7996110 | 0.86 | IDO1 (0.49) | IDO1SMN1; SMN2TSHRGAARCE1 | |
| SCHEMBL11800875 | 0.83 | IDO1 (0.65) | IDO1SMN1; SMN2MAPTKMT2APOLB | |
| SCHEMBL8003434 | 0.81 | IDO1 (0.50) | IDO1SMN1; SMN2GAAMAPTKMT2A | |
| SCHEMBL6430893 | 0.80 | ALDH1A1 (0.60) | SMN1; SMN2TSHRGAARCE1MAPT | |
| SCHEMBL8006520 | 0.80 | IDO1 (0.66) | IDO1SMN1; SMN2GAAMAPTKMT2A | |
| SCHEMBL8632649 | 0.80 | MAPT (0.50) | SMN1; SMN2TSHRGAAMAPTKMT2A | |
| SCHEMBL11575089 | 0.79 | ALDH1A1 (0.50) | IDO1GAAMAPTKMT2APOLB | |
| SCHEMBL30576385 | 0.79 | SMN1; SMN2 (0.56) | SMN1; SMN2TSHRGAARCE1MAPT | |
| SCHEMBL13292737 | 0.78 | SMN1; SMN2 (0.59) | SMN1; SMN2TSHRGAARCE1MAPT | |
| SCHEMBL7991044 | 0.78 | MAPT (0.55) | IDO1SMN1; SMN2MAPTKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117996-A | COMPLEXING; SEPARATION; PURIFICATION OF PROTEINS | NOVO NORDISK A/S (DK) | 2000-09-12 | — | — | US | disclosed |
| US-4086223-A | Asymmetrical 1:2-chromium complex azo dyestuffs | CIBA-GEIGY AG (CH) | 1978-04-25 | — | — | US | disclosed |