Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 6/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8003938 | 0.98 | CYP2D6 (0.35) | LMNATHRBKMT2AMEN1ALDH1A1 | |
| Ethylenediamine SCHEMBL6467532 | 0.80 | KDM4E (0.36) | LMNAKMT2AMEN1ALDH1A1GABRR1 | |
| Butylamine SCHEMBL3915440 | 0.79 | ALOX15 (0.38) | KMT2AMEN1ALDH1A1ALOX15CYP1A2 | |
| SCHEMBL30717989 | 0.74 | KDM4E (0.32) | ALDH1A1 | |
| SCHEMBL27936489 | 0.73 | ALDH1A1 (0.40) | LMNATHRBKMT2AMEN1ALDH1A1 | |
| SCHEMBL9253 | 0.72 | — | — | |
| SCHEMBL504094 | 0.71 | ALDH1A1 (0.38) | THRBALDH1A1 | |
| SCHEMBL10501371 | 0.71 | ALDH1A1 (0.38) | LMNATHRBKMT2AMEN1ALDH1A1 | |
| Carbamic Acid SCHEMBL8964476 | 0.70 | ACHE (0.41) | LMNAKMT2AMEN1ALDH1A1ALOX15 | |
| Tert-Butylamine SCHEMBL910388 | 0.70 | EPHX1 (0.37) | LMNAKMT2AMEN1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000027394-A1 | ACTIVATORS OF SOLUBLE GUANYLATE CYCLASE | UNIVERSITY COLLEGE LONDON (GB) | 2000-05-18 | — | — | WO | disclosed |