Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8004651 | 0.97 | HPGD (0.52) | HPGDKMT2AMEN1POLBMAPT | |
| SCHEMBL7992235 | 0.83 | LMNA (0.46) | KMT2AMEN1POLBMAPTALDH1A1 | |
| SCHEMBL8001897 | 0.79 | HDAC1 (0.48) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL10115015 | 0.70 | KMT2A (0.58) | HPGDKMT2AMEN1POLBSMN1; SMN2 | |
| SCHEMBL1893639 | 0.69 | MAPT (0.79) | HPGDKMT2AMEN1POLBMAPT | |
| SCHEMBL10115234 | 0.68 | MEN1 (0.58) | HPGDKMT2AMEN1POLBSMN1; SMN2 | |
| SCHEMBL9468747 | 0.68 | KMT2A (0.82) | KMT2AMEN1POLBMAPTSMN1; SMN2 | |
| SCHEMBL1006583 | 0.68 | MAPT (0.81) | HPGDKMT2AMEN1POLBMAPT | |
| SCHEMBL2011023 | 0.68 | MEN1 (1.00) | KMT2AMEN1POLBMAPTSMN1; SMN2 | |
| SCHEMBL14192656 | 0.66 | KMT2A (0.82) | KMT2AMEN1POLBMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119088-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |