Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CFTR | P13569 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | KCNT1 | Q5JUK3 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8004651 | 0.84 | HPGD (0.52) | LMNAMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL8003733 | 0.83 | HPGD (0.51) | LMNAMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL8006929 | 0.80 | KLK7 (0.40) | LMNAMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL1007557 | 0.69 | MAPT (0.73) | LMNAMAPTKMT2AMEN1POLB | |
| SCHEMBL13390934 | 0.67 | KMT2A (0.68) | LMNAMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL8930613 | 0.64 | CRHBP (0.64) | LMNAMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL9468747 | 0.63 | KMT2A (0.82) | LMNAMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL9471095 | 0.63 | KMT2A (0.63) | LMNAMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL18500908 | 0.62 | ALDH1A1 (0.74) | LMNAMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL2011023 | 0.62 | MEN1 (1.00) | LMNAMAPTKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119088-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |