Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | DPEP1 | P16444 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.40 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4740680 | 0.79 | CYP3A4 (0.51) | NPC1RAB9ADPEP1EPHX2EPHX1 | |
| SCHEMBL3856454 | 0.79 | CYP3A4 (0.51) | NPC1RAB9ADPEP1EPHX2EPHX1 | |
| SCHEMBL4743549 | 0.77 | CYP3A4 (0.53) | NPC1RAB9ADPEP1EPHX2 | |
| SCHEMBL5698294 | 0.77 | KDM4E (0.52) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL8416201 | 0.76 | KDM4E (0.44) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL563351 | 0.76 | KDM4E (0.51) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL8865007 | 0.76 | KDM4E (0.55) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL7971777 | 0.76 | KDM4E (0.55) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL3817101 | 0.76 | KDM4E (0.55) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL7328223 | 0.76 | KDM4E (0.51) | KDM4EMEN1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699694-B1 | Comb polymers | ROEHM GMBH (DE) | 2000-01-05 | — | — | EP | disclosed |