Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | SMPD2 | O60906 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8865001 | 1.00 | KDM4E (0.55) | KDM4EPTPN1ALDH1A1MAPTHPGD | |
| SCHEMBL5698294 | 0.85 | KDM4E (0.52) | KDM4EALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL3817099 | 0.84 | KDM4E (0.55) | KDM4EALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL563351 | 0.84 | KDM4E (0.51) | KDM4EALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL7328223 | 0.84 | KDM4E (0.51) | KDM4EALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL3817101 | 0.84 | KDM4E (0.55) | KDM4EALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL7328215 | 0.84 | KDM4E (0.51) | KDM4EALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL7971777 | 0.84 | KDM4E (0.55) | KDM4EALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL7275466 | 0.83 | KDM4E (0.50) | KDM4EALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL7275461 | 0.83 | KDM4E (0.50) | KDM4EALDH1A1MAPTHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646313-A | PREPARING ENKEPHALINASE INHIBITORS | SOCIETE CIVILE BIOPROJET (FR) | 1997-07-08 | — | — | US | disclosed |
| US-5612371-A | ENZYME INHIBITORS | SOCIETE CIVILE BIOPROJECT (FR) | 1997-03-18 | — | — | US | disclosed |