Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 14/20 | 0.54 |
| ▸ | MMP8 | P22894 | 12/20 | 0.54 |
| ▸ | MMP13 | P45452 | 12/20 | 0.54 |
| ▸ | MMP9 | P14780 | 11/20 | 0.54 |
| ▸ | BMP1 | P13497 | 4/20 | 0.51 |
| ▸ | MMP1 | P03956 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8016814 | 0.90 | MMP2 (0.57) | MMP2MMP8MMP13MMP9BMP1 | |
| SCHEMBL8019045 | 0.86 | MMP2 (0.57) | MMP2MMP8MMP13MMP9BMP1 | |
| SCHEMBL6438866 | 0.86 | MMP2 (0.60) | MMP2MMP8MMP13MMP9BMP1 | |
| SCHEMBL8012143 | 0.85 | MMP2 (0.54) | MMP2MMP8MMP13MMP9BMP1 | |
| SCHEMBL8015460 | 0.85 | MMP2 (0.55) | MMP2MMP8MMP13MMP9BMP1 | |
| SCHEMBL8015005 | 0.85 | MMP2 (0.55) | MMP2MMP8MMP13MMP9BMP1 | |
| SCHEMBL27540117 | 0.84 | BMP1 (0.60) | MMP2MMP8MMP13MMP9BMP1 | |
| SCHEMBL8012375 | 0.83 | MMP2 (0.51) | MMP2MMP8MMP13MMP9BMP1 | |
| SCHEMBL27503556 | 0.83 | MMP2 (0.57) | MMP2MMP8MMP13MMP9BMP1 | |
| SCHEMBL8012982 | 0.83 | MMP2 (0.61) | MMP2MMP8MMP13MMP9BMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153609-A | Arylsulfonylamino hydroxamic acid derivatives | PFIZER INC (US) | 2000-11-28 | — | — | US | disclosed |