Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12169135 | 0.83 | SIGMAR1 (0.37) | SIGMAR1DRD2HPGDKDM4EALDH1A1 | |
| SCHEMBL1419929 | 0.81 | ALDH1A1 (0.49) | SIGMAR1DRD2HPGDKDM4EHCAR2 | |
| SCHEMBL7897120 | 0.81 | SIGMAR1 (0.36) | SIGMAR1DRD2HPGDKDM4EALDH1A1 | |
| SCHEMBL9875527 | 0.81 | SIGMAR1 (0.51) | SIGMAR1DRD2HPGDKDM4EHCAR3 | |
| SCHEMBL6999022 | 0.79 | PTGS2 (0.41) | SIGMAR1DRD2HPGDKDM4EALDH1A1 | |
| SCHEMBL286520 | 0.79 | HPGD (0.55) | SIGMAR1DRD2HPGDKDM4EALDH1A1 | |
| SCHEMBL286625 | 0.78 | SIGMAR1 (0.36) | SIGMAR1DRD2HPGDKDM4EALDH1A1 | |
| SCHEMBL286370 | 0.77 | MAPT (0.38) | SIGMAR1ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL7001594 | 0.77 | SIGMAR1 (0.34) | SIGMAR1DRD2HPGDKDM4EALDH1A1 | |
| SCHEMBL1419953 | 0.77 | HSD17B10 (0.41) | ALDH1A1TDP1MEN1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009158393-A1 | 1, 2 DISUBSTITUTED HETEROCYCLIC COMPOUNDS | ENVIVO PHARMACEUTICALS, INC. (US) | 2009-12-30 | — | — | WO | disclosed |