Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.48 |
| ▸ | ESR1 | P03372 | 3/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | EBP | Q15125 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8004275 | 0.89 | ESR1 (0.54) | LTA4HESR1ESR2KCNH2SMPD1 | |
| SCHEMBL8004295 | 0.85 | ESR1 (0.55) | LTA4HMCHR1ESR1ESR2ACHE | |
| SCHEMBL4651133 | 0.82 | MCHR1 (0.58) | LTA4HMCHR1ESR1ESR2MMP1 | |
| SCHEMBL11500173 | 0.80 | LTA4H (0.49) | LTA4HMCHR1ESR1ESR2KMT2A | |
| SCHEMBL11191693 | 0.80 | ESR1 (0.49) | LTA4HESR1ESR2MEN1KMT2A | |
| SCHEMBL8003918 | 0.79 | LTA4H (0.60) | LTA4HESR1ESR2KCNH2EBP | |
| SCHEMBL8004280 | 0.73 | ESR1 (0.70) | LTA4HESR1ESR2TSHREBP | |
| SCHEMBL6595246 | 0.73 | LTA4H (0.59) | LTA4HESR1ESR2EBPSIGMAR1 | |
| SCHEMBL11188218 | 0.71 | MCHR1 (0.46) | MCHR1ESR1ESR2MEN1KMT2A | |
| SCHEMBL8015671 | 0.71 | EBP (0.67) | LTA4HESR1ESR2EBPSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114336-A | Cosmetic composition containing a neuropeptide Y receptor antagonist | SANOFI (FR) | 2000-09-05 | — | — | US | disclosed |