Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 12/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.55 |
| ▸ | EBP | Q15125 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8004280 | 0.88 | ESR1 (0.70) | ESR1ESR2EBPSIGMAR1LTA4H | |
| SCHEMBL8004293 | 0.85 | LTA4H (0.53) | ESR1ESR2EBPSIGMAR1MCHR1 | |
| SCHEMBL4651133 | 0.83 | MCHR1 (0.58) | ESR1ESR2MCHR1LTA4H | |
| SCHEMBL17152127 | 0.81 | ESR1 (0.69) | ESR1ESR2EBPSIGMAR1LTA4H | |
| SCHEMBL8003921 | 0.77 | EBP (0.78) | ESR1ESR2EBPSIGMAR1MCHR1 | |
| SCHEMBL6756238 | 0.74 | ESR1 (0.80) | ESR1ESR2EBPSIGMAR1 | |
| SCHEMBL13109358 | 0.74 | EBP (0.74) | ESR1ESR2EBPSIGMAR1 | |
| SCHEMBL8004275 | 0.73 | ESR1 (0.54) | ESR1ESR2LTA4H | |
| SCHEMBL6756233 | 0.72 | ESR1 (0.68) | ESR1ESR2EBPSIGMAR1LTA4H | |
| SCHEMBL11188218 | 0.72 | MCHR1 (0.46) | ESR1ESR2MCHR1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114336-A | Cosmetic composition containing a neuropeptide Y receptor antagonist | SANOFI (FR) | 2000-09-05 | — | — | US | disclosed |