Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL68843 | 0.81 | LMNA (0.46) | TSHRKDM4EGMNNLMNAPMP22 | |
| SCHEMBL38319 | 0.81 | LMNA (0.46) | TSHRKDM4EGMNNLMNAPMP22 | |
| SCHEMBL25659463 | 0.78 | FFAR3 (0.38) | TSHRKDM4EGMNNLMNAPMP22 | |
| SCHEMBL18640563 | 0.74 | ALDH1A1 (0.33) | TSHRKDM4EGMNNLMNAPMP22 | |
| SCHEMBL21987293 | 0.72 | PPM1B (0.37) | TSHR | |
| SCHEMBL25659464 | 0.71 | FFAR3 (0.35) | TSHRKDM4EGMNNLMNAPMP22 | |
| SCHEMBL10669324 | 0.71 | LMNA (0.42) | TSHRKDM4EGMNNLMNAPMP22 | |
| SCHEMBL70127 | 0.71 | LMNA (0.42) | TSHRKDM4EGMNNLMNAPMP22 | |
| SCHEMBL14783405 | 0.70 | — | — | |
| SCHEMBL16841846 | 0.70 | GMNN (0.37) | TSHRKDM4EGMNNLMNAPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6077952-A | Cephaloporins and homologues | PFIZER INC. (US) | 2000-06-20 | — | — | US | disclosed |
| US-6020329-A | Cephaloporins and homologues, preparations and pharmaceutical compositions | PZIFER INC. (US) | 2000-02-01 | — | — | US | disclosed |
| US-6001997-A | Cephalosporins and homologues, preparations and pharmaceutical compositions | BATESON JOHN HARGREAVES (GB) | 1999-12-14 | — | — | US | disclosed |
| EP-0540609-A1 | CEPHALOSPORINS AND HOMOLOGUES, PREPARATIONS AND PHARMACEUTICAL COMPOSITIONS | PFIZER INC. (US) | 1993-05-12 | — | — | EP | disclosed |
| WO-1992001696-A1 | CEPHALOSPORINS AND HOMOLOGUES, PREPARATIONS AND PHARMACEUTICAL COMPOSITIONS | BEECHAM GROUP PLC (GB) | 1992-02-06 | — | — | WO | disclosed |