Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29067330 | 0.76 | EPHX2 (0.57) | KMT2AHTTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL10458447 | 0.74 | KDM4E (0.72) | KMT2AHTTMAPK1HPGDSMN1; SMN2 | |
| SCHEMBL13480553 | 0.73 | TAS1R3 (0.60) | CASRKMT2AHTTMAPK1TP53 | |
| SCHEMBL88302 | 0.73 | HTR2A (0.45) | KMT2ATSHRCYP1A2MEN1MAPT | |
| SCHEMBL1567087 | 0.73 | HTR2A (0.45) | KMT2ATSHRMAPT | |
| SCHEMBL29579635 | 0.73 | HTR2A (0.45) | KMT2ATSHRCYP1A2MEN1MAPT | |
| SCHEMBL7995243 | 0.72 | NPC1 (0.57) | CASRKMT2AHTTMAPK1TP53 | |
| SCHEMBL8598568 | 0.72 | NPC1 (0.52) | CASRKMT2AHTTMAPK1TP53 | |
| SCHEMBL21895871 | 0.72 | MTNR1A (0.49) | KMT2APOLB | |
| SCHEMBL9499589 | 0.71 | SOAT1 (0.51) | KMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6060484-A | Anti-viral method | ELI LILLY AND COMPANY (US) | 2000-05-09 | — | — | US | disclosed |