Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8004007 | 0.83 | C5AR1 (0.37) | KCNQ3KCNQ2CA2CA4C5AR1 | |
| SCHEMBL9018656 | 0.82 | POLB (0.37) | CTSDMEN1KMT2ACA2CA4 | |
| SCHEMBL8004812 | 0.71 | KCNQ3 (0.42) | KCNQ3KCNQ2CA2CA4 | |
| SCHEMBL7995263 | 0.69 | SLC6A4 (0.48) | KCNQ3KCNQ2CA2CA4 | |
| SCHEMBL8004004 | 0.67 | KCNQ3 (0.39) | MEN1KMT2AKCNQ3KCNQ2CA2 | |
| SCHEMBL8363877 | 0.67 | SLC9A1 (0.56) | — | |
| Hydrochloric Acid SCHEMBL8743851 | 0.67 | SLC9A1 (0.55) | — | |
| SCHEMBL9018660 | 0.65 | POLB (0.33) | MEN1KMT2AKCNQ3KCNQ2CA2 | |
| SCHEMBL7995261 | 0.65 | TTR (0.61) | CA2CA4 | |
| SCHEMBL29625906 | 0.64 | BRD4 (0.46) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022899-A | EFFECTIVE INHIBITORS OF THE CELLULAR SODIUM PROTON ANTIPORTER | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-02-08 | — | — | US | claimed |
| US-6022899-A | EFFECTIVE INHIBITORS OF THE CELLULAR SODIUM PROTON ANTIPORTER | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-02-08 | — | — | US | disclosed |
| US-5753710-A | INHIBITORS OF THE CELLULAR SODIUM PROTON ANTIPORTER | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-05-19 | — | — | US | disclosed |