Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28738313 | 1.00 | BRD4 (0.46) | BRD4L3MBTL1SMN1; SMN2MAOBMEN1 | |
| SCHEMBL9178435 | 0.90 | L3MBTL1 (0.49) | L3MBTL1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL8769337 | 0.84 | POLB (0.56) | BRD4L3MBTL1SMN1; SMN2MAOBMEN1 | |
| SCHEMBL29181894 | 0.81 | MEN1 (0.58) | L3MBTL1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL8005449 | 0.78 | TTR (0.61) | L3MBTL1SMN1; SMN2MAOBMEN1KMT2A | |
| SCHEMBL7995261 | 0.78 | TTR (0.61) | BRD4POLBGCK | |
| SCHEMBL8070954 | 0.78 | PKM (0.50) | RAB9A | |
| SCHEMBL2650962 | 0.78 | SMN1; SMN2 (0.65) | L3MBTL1SMN1; SMN2POLBHTT | |
| SCHEMBL8942128 | 0.77 | PTGS1 (0.55) | BRD4SMN1; SMN2MAOBMEN1KMT2A | |
| SCHEMBL6712174 | 0.77 | MAOB (0.47) | BRD4SMN1; SMN2MAOBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114423743-A | Triazine derivatives for the treatment of diseases associated with neurotrophic factors | 阿泽克制药公司 | 2022-04-29 | — | — | CN | disclosed |